ArticleDigestive diseases and sciences2008
Role of procalcitonin in infectious gastroenteritis and inflammatory bowel disease.
Article in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 36 citations in OpenAlex.
- Article
- The Significance of Inflammatory Markers in Pediatric Patients with Acute Gastroenteritis Presenting to the Emergency Department.Children (Basel, Switzerland) · 2025Article
- Procalcitonin and C-Reactive Protein as Diagnostic Biomarkers for Bacterial Gastroenteritis: A Retrospective Analysis.Journal of clinical medicine · 2025Article
- The Prognostic Role of Serum Procalcitonin for Adult Patients with Acute Diarrhea in the Emergency Department.Diagnostics (Basel, Switzerland) · 2025Article
- Evaluation of Fecal Calprotectin, Serum C-Reactive Protein, Erythrocyte Sedimentation Rate, Seromucoid and Procalcitonin in the Diagnostics and Monitoring of Crohn's Disease in Children.Journal of clinical medicine · 2022Article
- Predictive Value of Procalcitonin in Acute Severe Ulcerative Colitis: Not Quite PerfeCT?Digestive diseases and sciences · 2019Article
- Relationship between serum procalcitonin level and chronic obstructive pulmonary disease.Journal of family medicine and primary care · 2019Article
- Observational
- Procalcitonin in inflammatory bowel disease: Drawbacks and opportunities.World journal of gastroenterology · 2017Review
- Diagnostic yield of stool culture and predictive factors for positive culture in patients with diarrheal illness.Medicine · 2017Article
- Usefulness of Measuring Serum Procalcitonin Levels in Patients with Inflammatory Bowel Disease.Gut and liver · 2016Article
- Sensitivity and specificity of procalcitonin to determine etiology of diarrhea in children younger than 5 years.Materia socio-medica · 2014Article
- Clinical significance of serum procalcitonin in patients with ulcerative colitis.World journal of gastroenterology · 2013Article
- Use of plasma procalcitonin levels as an adjunct to clinical microbiology.Journal of clinical microbiology · 2010Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimWe have evaluated procalcitonin (PCT) as a diagnostic marker for bacterial gastroenteritis (GE) and as a disease activity marker in inflammatory bowel disease (IBD) patients.
methodsThis was a prospective single-center study performed over a 1-year period. Venous blood samples were drawn from hospitalized patients with acute GE and tested for PCT, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and total white cell count (TWC); stools from the same patients were tested for standard pathogens. Venous blood samples from patients with IBD were tested for PCT, CRP, ESR, and platelet count. The PCT level was measured using an immunofluorescent assay, with normal being defined as <0.5 ng/ml.
resultsThe GE arm of study consisted of 81 patients, 18.5% of whom were diagnosed with bacterial GE. The PCT and CRP levels were good diagnostic markers of bacterial GE, with an area under the curve (AUC) of 0.727 [95% confidence interval (CI) 0.580-0.874] and 0.786 (95% CI 0.627-0.946), respectively. An elevated PCT > or =0.5 ng/ml was associated with a 13-fold increased risk of renal impairment. The IBD arm of study consisted of 72 IBD patients. The PCT levels were not significantly different between active and inactive IBD in this patient cohort.
conclusionOur results indicate that PCT and CRP are comparably good diagnostic markers of bacterial GE but that PCT is not useful as in monitoring disease activity in patients with IBD.
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