Evidence map›Paper›PMID 18415076›Full record

ArticleDer Orthopade2008

[Oral anticoagulation after major hip or knee replacement surgery: a process-driven managerial pharmacoeconomic analysis in German hospitals].

T Wilke, K Neumann, U Klapper, I Messer, A Werner, U Seidel, D Röleke

Abstract readEnglish AbstractMulticenter Study
PubMed Publisher
In one paragraph

Article in Der Orthopade, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

T WilkeInstitut für Pharmakoökonomie und Arzneimittellogistik, Hochschule Wismar, PF 1210, 23952 Wismar. thomas.wilke@hs-wismar.de
K Neumann
U Klapper
I Messer
A Werner
U Seidel
D Röleke
Wismar University of Applied Sciences · DEAsklepios · DEBoehringer Ingelheim (Australia) · AUKnappschaftskrankenhaus Recklinghausen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe thrombin inhibitor dabigatranetexilat is used for prophylaxis of venous thromboembolism after total hip or knee replacement surgery (THR/TKR). Patients can take it orally in hospitals.

methodIn a managerial pharmacoeconomic analysis of six German acute-care hospitals and six German rehabilitation hospitals, the use of dabigatranetexilat was compared with the use of low-molecular-weight heparins.

resultsThe analysis showed that the new drug led to an economic advantage for an acute-care hospital of 2.43 euro per patient per day. In a rehabilitation hospital, the use of dabigatranetexilat led to an economic advantage of 1.40 euro per patient per day.

conclusionThese results have direct implications for drug decisions in hospitals. To demonstrate that fact, the price difference between dabigatranetexilat and low-molecular-weight heparins was derived to lead exactly to their"economic neutrality" from the hospital's point of view.

Indexed as

Economics, PharmaceuticalAdministration, OralAnticoagulantsArthroplasty, Replacement, HipArthroplasty, Replacement, KneeBenzimidazolesDabigatranGermanyHealth Care CostsHeparin, Low-Molecular-WeightHumansPostoperative ComplicationsPyridinesRetrospective StudiesTreatment OutcomeVenous ThromboembolismAnticoagulantsBenzimidazolesDabigatranHeparin, Low-Molecular-WeightPyridines

Identifiers

PMID18415076
OpenAlexW1495226078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.