ArticleJournal of neuro-oncology2008
Outcome of pediatric pineoblastoma after surgery, radiation and chemotherapy.
Article in Journal of neuro-oncology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 70 citations in OpenAlex.
- Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials.Acta neuropathologica · 2020Trial
- Pineal parenchymal tumors. Management with interstitial iodine-125 radiosurgery.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2010Trial
- Results of the treatment of pineal tumors in children: the Lyon experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Review
- Prognostic factors and outcome of pineoblastoma: 10 years single-center experience.Journal of the Egyptian National Cancer Institute · 2021Article
- Surgical techniques in the management of supratentorial pediatric brain tumors: 10 years' experience at a tertiary care center in the Middle East.Surgical neurology international · 2021Article
- Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study.Acta neuropathologica · 2020Article
- Development and Validation of a Prognostic Nomogram to Predict Cancer-Specific Survival in Adult Patients With Pineoblastoma.Frontiers in oncology · 2020Article
- Article
- Pineal region tumors: a simplified management scheme.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
- Tackling a recurrent pinealoblastoma.Case reports in oncological medicine · 2014Article
- Relapse patterns in pediatric embryonal central nervous system tumors.Journal of neuro-oncology · 2013Article
- Primary pineal tumors: outcome and prognostic factors--a study from the Rare Cancer Network (RCN).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2012Article
- Long term outcome of adolescent and adult patients with pineal parenchymal tumors treated with fractionated radiotherapy between 1982 and 2003--a single institution's experience.Radiation oncology (London, England) · 2010Article
- Article
- Pediatric pineoblastoma: A pooled outcome study of North American and Australian therapeutic data.Neuro-oncology advancesArticle
- Survival and associated predictors for patients with pineoblastoma or pineal parenchymal tumors of intermediate differentiation older than 3 years: Insights from the National Cancer Database.Neuro-oncology advancesArticle
- Extraneural Metastases in an Operated Case of Pinealoblastoma Identified on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPineoblastomas are a category of supratentorial primitive neuroectodermal tumors (sPNETs) occurring in the pineal gland; some studies support the impression that patients with pineoblastomas have a worse prognosis than those with other sPNETs.
methodsWe reviewed the medical records and tissue sections of all patients with the diagnosis of pineoblastoma that were treated at the Dana-Farber Cancer Institute/Children's Hospital Boston Pediatric Brain Tumor Program between 1986 and 2005.
resultsThirteen patients with the pathologic diagnosis of pineoblastoma were treated at our Hospital; 11 of these cases had complete records suitable for study. The median age was 8 years 8 months (5 F, 6 M). Surgical, radiation and chemotherapeutic regimens varied from case to case. Three patients had gross total resection and are alive and free of disease, versus four of eight with subtotal resection or biopsy only. Patients who received CSI and multi-agent chemotherapy had improved overall survival.
conclusionsSeven of eleven patients with pineoblastoma are currently alive and free of disease, reflecting an improved outcome and longer survival than previously appreciated. Gross total surgical resection appeared to correlate with improved survival, as did treatment with craniospinal irradiation and multi-agent chemotherapy. Further study of this group of patients as a distinct diagnostic entity will be necessary to determine optimal therapy.
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