ArticleEnvironmental health perspectives2008
Risk of childhood cancers associated with residence in agriculturally intense areas in the United States.
Article in Environmental health perspectives, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Passive environmental residential exposure to agricultural pesticides and hematological malignancies in the general population: a systematic review.Environmental science and pollution research international · 2021Pooled it
- Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies.International journal of cancer · 2026Article
- Harvesting Risk: An Ecologic Study of Agricultural Practices and Patterns and Melanoma Incidence in Pennsylvania.JCO clinical cancer informatics · 2025Article
- Cumulative Exposure to Unconventional Natural Gas Development and the Risk of Childhood Cancer: A Registry-Based Case-Control Study.International journal of environmental research and public health · 2025Article
- Reducing education inequalities through cloud-enabled live-cell biotechnology.Trends in biotechnology · 2025Review
- Residential proximity to agricultural herbicide and fungicide applications and dust levels in homes of California children.Environment international · 2024Article
- Review
- Response to "Comment on 'Association between Residential Proximity to Viticultural Areas and Childhood Acute Leukemia Risk in Mainland France: GEOCAP Case-Control Study, 2006-2013'".Environmental health perspectives · 2024Article
- Association between Residential Proximity to Viticultural Areas and Childhood Acute Leukemia Risk in Mainland France: GEOCAP Case-Control Study, 2006-2013.Environmental health perspectives · 2023Article
- Cloud-controlled microscopy enables remote project-based biology education in underserved Latinx communities.Heliyon · 2022Article
- Incidence and Risk Factors of Acute Leukemias in Armenia: A Population-Based Study.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Residential proximity to croplands at birth and childhood leukaemia.Environmental health : a global access science source · 2022Article
- Geospatial Distribution of Age-Adjusted Incidence of the Three Major Types of Pediatric Cancers and Waterborne Agrichemicals in Nebraska.GeoHealth · 2022Article
- Residential proximity to agriculture and risk of childhood leukemia and central nervous system tumors in the Danish national birth cohort.Environment international · 2020Article
- Prenatal pesticide exposure and childhood leukemia - A California statewide case-control study.International journal of hygiene and environmental health · 2020Article
- Residential mobility in early childhood and the impact on misclassification in pesticide exposures.Environmental research · 2019Article
- Baseballs, tennis balls, livestock farm manure, the IDH1 mutation, endothelial cell proliferation and hypoxic pseudopalisading (granulomatous) necrosis:Open veterinary journal · 2019Review
- Livestock and poultry density and childhood cancer incidence in nine states in the USA.Environmental research · 2017Article
- Pesticide Exposure and Head and Neck Cancers: A Case-Control Study in an Agricultural Region.Iranian journal of otorhinolaryngology · 2017Article
- The Association between Lifestyle, Occupational, and Reproductive Factors and Colorectal Cancer RiskAsian Pacific journal of cancer prevention : APJCP · 2017Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe potential for widespread exposure to agricultural pesticides through drift during application raises concerns about possible health effects to exposed children living in areas of high agricultural activity.
objectivesWe evaluated whether residence in a county with greater agricultural activity was associated with risk of developing cancer in children < 15 years of age.
methodsIncidence data for U.S. children 0-14 years of age diagnosed with cancer between 1995 and 2001 were provided by member registries of the North American Association of Central Cancer Registries. We determined percent cropland for each county using agricultural census data, and used the overall study distribution to classify agriculturally intense counties. We estimated odds ratios and 95% confidence intervals for all ages and 5-year age groups for total cancers and selected cancer sites using logistic regression.
resultsOur study results showed statistically significant increased risk estimates for many types of childhood cancers associated with residence at diagnosis in counties having a moderate to high level of agricultural activity, with a remarkably consistent dose-response effect seen for counties having >or= 60% of the total county acreage devoted to farming. Risk for different cancers varied by type of crop.
conclusionsAlthough interpretation is limited by the ecologic design, in this study we were able to evaluate rarer childhood cancers across a diverse agricultural topography. The findings of this exploratory study support a continued interest in the possible impact of long-term, low-level pesticide exposure in communities located in agriculturally intense areas.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.