Evidence map›Paper›PMID 18414502›Full record

ReviewNature reviews. Microbiology2008

Emerging and re-emerging rickettsioses: endothelial cell infection and early disease events.

David H Walker, Nahed Ismail

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 179 papers.

0numbers the graph read from it
0cells of the map it votes in
179citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

179 citing papers in PubMed, 298 citations in OpenAlex.

  1. Review
  2. Article
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  6. Review
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  9. Article
  10. Review
  11. Hybrid capture RNA-seq defines temporal gene expression inbioRxiv : the preprint server for biology · 2026
    Article
  12. Article
  13. Facultative mutualism betweenISME communications · 2026
    Article
  14. Review
  15. Wild mammals as hosts ofInternational journal for parasitology. Parasites and wildlife · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Infection and immunity · 2025
    Article
  20. Article

119 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David H WalkerDepartment of Pathology, University of Texas, Medical Branch, Galveston, Texas 77555-0609, USA. dwalker@utmb.edu
Nahed Ismail
The University of Texas Medical Branch at Galveston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rickettsiae cause some of the most severe human infections, including epidemic typhus and Rocky Mountain spotted fever. Substantial progress has been made in research into the genomics, vector relationships, pathogenesis and immunity of these obligate, intracellular, arthropod-transmitted bacteria. This Review summarizes our understanding of the early and late events in pathogenesis and immunity, modulation of the host response to rickettsial infection by the vector, host defence, virulence mechanisms and rickettsial manipulation of host cells.

Indexed as

Endothelial CellsHost-Pathogen InteractionsHumansRickettsiaRickettsia InfectionsVirulence

Identifiers

PMID18414502
OpenAlexW2039400507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.