GuidelineGenetics in medicine : official journal of the American College of Medical Genetics2008
Clinical genetics evaluation in identifying the etiology of autism spectrum disorders.
Guideline in Genetics in medicine : official journal of the American College of Medical Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Parental Perspectives on Early Life Screening and Genetic Testing for ASD: A Systematic Review.Journal of autism and developmental disorders · 2025Pooled it
- Interpretable Disorder Signatures: Probing Neural Latent Spaces for Schizophrenia, Alzheimer's, and Autism Stratification.Brain sciences · 2025Article
- From wings to whiskers to stem cells: why every model matters in fragile X syndrome research.Journal of neurodevelopmental disorders · 2024Review
- Diagnosis and Assessment of Autism Spectrum Disorder in South Korea.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2024Article
- Knowledge, attitudes and experiences of genetic testing for autism spectrum disorders among caregivers, patients, and health providers: A systematic review.World journal of psychiatry · 2023Article
- Working Memory Training in Youth With Autism, Fragile X, and Intellectual Disability: A Pilot Study.American journal on intellectual and developmental disabilities · 2022Article
- An ethical analysis of divergent clinical approaches to the application of genetic testing for autism and schizophrenia.Human genetics · 2022Article
- Article
- Clinical Assessment, Genetics, and Treatment Approaches in Autism Spectrum Disorder (ASD).International journal of molecular sciences · 2020Review
- Investigating Potential Biomarkers in Autism Spectrum Disorder.Frontiers in integrative neuroscience · 2019Article
- Diagnostic and Severity-Tracking Biomarkers for Autism Spectrum Disorder.Journal of molecular neuroscience : MN · 2018Review
- Autism spectrum disorder early in development associated with CHD8 mutations among two Chinese children.BMC pediatrics · 2018Article
- Is it time to retire fragile X testing as a first-tier test for developmental delay, intellectual disability, and autism spectrum disorder?Genetics in medicine : official journal of the American College of Medical Genetics · 2017Article
- Mutation analysis of theBalkan journal of medical genetics : BJMG · 2016Article
- Elucidating Genetic Counseling Outcomes from the Perspective of Genetic Counselors.Journal of genetic counseling · 2016Article
- A Child with Kabuki Syndrome and Autism Spectrum Disorder.Noro psikiyatri arsivi · 2016Article
- Clinical Genetic Aspects of ASD Spectrum Disorders.International journal of molecular sciences · 2016Review
- Neuroimaging endophenotypes in autism spectrum disorder.CNS spectrums · 2015Review
- Integrated analysis of whole-exome sequencing and transcriptome profiling in males with autism spectrum disorders.Molecular autism · 2015Article
- Uptake and Diagnostic Yield of Chromosomal Microarray in an Australian Child Development Clinic.Children (Basel, Switzerland) · 2014Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The autism spectrum disorders are a collection of conditions, which have, in common, impaired socialization and communication in association with stereotypic behaviors. The reported incidence of autism spectrum disorders has increased markedly over the past decade. In addition, a large amount of attention has been paid to these conditions among lay and professional groups. These influences have resulted in a marked increase in the number of referrals to clinical geneticists for evaluation of persons with autism spectrum disorders. The primary role of the geneticist in this process is to define etiology, if possible, and to provide counseling and contribute to case management based on the results of such investigations. In deciding upon the appropriate evaluation scheme for a particular patient, the geneticist must consider a host of different factors. Such considerations would include (1) Assuring an accurate diagnosis of autism before proceeding with any investigation. (2) Discussing testing options, diagnostic yields, and patient investment before proceeding with an evaluation. (3) Communication and coordination with the patient's medical home. (4) Assessing the continuously expanding and evolving list of available laboratory testing modalities in light of evidence-based medicine. (5) Recognizing expanded phenotypes of well-described syndromic and metabolic conditions that encompass autism spectrum disorders. (6) Defining an individualized evaluation scheme based on the unique history and clinical features of a given patient. The guidelines in this article have been developed to assist the clinician in the consideration of these factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.