Evidence map›Paper›PMID 18413710›Full record

ArticleGenes & development2008

pRb and condensin--local control of global chromosome structure.

Brigitte D Lavoie

Open access · diamondAbstract readComment
In one paragraph

Article in Genes & development, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Brigitte D LavoieDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada. brigitte.lavoie@utoronto.ca
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rb mutants exhibit aneuploidy and aberrant chromosome structure during mitosis. In this issue of Genes & Development, a new paper from Longworth and colleagues (1011-1024) describes both physical and functional interactions between Drosophila Rbf1 and the dCAP-D3 subunit of condensin II. This work directly implicates the Rb family proteins in mitotic chromosome condensation and suggests that a failure in targeting condensin II to chromatin underlies the aneuploidy in rbf1 mutants.

Indexed as

Adenosine TriphosphatasesAnimalsChromosome StructuresDNA-Binding ProteinsDrosophila ProteinsHumansMitosisModels, BiologicalMultiprotein ComplexesRetinoblastoma ProteinTranscription FactorsAdenosine Triphosphatasescondensin complexesDNA-Binding ProteinsDrosophila ProteinsMultiprotein ComplexesRbf protein, DrosophilaRetinoblastoma ProteinTranscription Factors

Identifiers

PMID18413710
PMCPMC2732393
OpenAlexW2029140395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.