Evidence map›Paper›PMID 18413004›Full record

ArticleEpidemiology and infection2009

Socioeconomic disparities in the seroprevalence of cytomegalovirus infection in the US population: NHANES III.

J B Dowd, A E Aiello, D E Alley

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 3 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 3 syntheses or guidelines pooled it, 209 citations in OpenAlex.

  1. Rethinking immune studies: population-level immune variations and the path forward.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Pooled it
  2. Viruses and celiac disease: what do we know ?Clinical and experimental medicine · 2023
    Pooled it
  3. Pooled it
  4. The influence of Epstein-Barr virus and cytomegalovirus on childhood respiratory health: A population-based prospective cohort study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2020
    Trial
  5. Trial
  6. Article
  7. Observational
  8. Acyclic graphs to define models of relationships between human cytomegalovirus, cardiovascular disease and all-cause mortality in UK Biobank.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Association between cytomegalovirus infection and dyslipidemia in US: an NHANES analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Chronic Stress and Latent Virus Reactivation: Effects on Immune Aging, Chronic Disease Morbidity, and Mortality.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
    Article

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

J B DowdDepartment of Epidemiology, Center for Social Epidemiology & Population Health, School of Public Health, University of Michigan, Ann Arbor, MI, USA. jenndowd@umich.edu
A E Aiello
D E Alley
University of Michigan–Ann Arbor · USUniversity of Pennsylvania · US

Funding

Social-biological predictors of heterogeneity in CVD risk in African AmericansP60MD002249 · NIMHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIEZ ROUX, ANA VICTORIA, MENDES DE LEON, CARLOS F. · 2007 to 2016
$15.0M
RESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2M
NIA NIH HHS T32 AG000037NIMHD NIH HHS P60 MD002249
6 · The paper itself

Abstract

There is a strong relationship between socioeconomic status (SES) and health outcomes in the United States, although the mechanisms are poorly understood. Increasing evidence points to links between lifelong exposure to infectious disease and subsequent chronic disease. Exposure and susceptibility to infections may be one way SES affects long-term health, although little population-based research to date has examined social patterning of infections in the United States. This paper tests the relationship between income, education, race/ethnicity and seroprevalence of cytomegalovirus (CMV) infection at different ages in a representative sample of the US population, and tests potential mediators for these relationships. The study finds significant racial and socioeconomic disparities in CMV seroprevalence beginning at early ages and persisting into middle age. Potential exposures do not explain the relationship between SES and CMV positivity. Because reactivation of latent CMV infections may contribute to chronic disease and immune decline later in life, future research should determine the exposure or susceptibility pathways responsible for these disparities in the prevalence of CMV infection.

Indexed as

Socioeconomic FactorsAdolescentAdultAgedAged, 80 and overAge FactorsChildCytomegalovirus InfectionsEducationFemaleHumansIncomeMaleMiddle AgedNutrition SurveysRacial Groups

Identifiers

PMID18413004
PMCPMC3806637
OpenAlexW2141683146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.