How highly charged anionic lipids bind and regulate ion channels.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

36 citing papers in PubMed.

1. Anionic lipids modulate the membrane localization and conformational dynamics of KirBac1.1 slide helix during lipid-dependent activation.The Biochemical journal · 2025
   Article
2. The Influence of Phosphoinositide Lipids in the Molecular Biology of Membrane Proteins: Recent Insights from Simulations.Journal of molecular biology · 2025
   Review
3. Phosphatidic acid is an endogenous negative regulator of PIEZO2 channels and mechanical sensitivity.Nature communications · 2024
   Article
4. Phosphatidic acid is an endogenous negative regulator of PIEZO2 channels and mechanical sensitivity.bioRxiv : the preprint server for biology · 2024
   Article
5. Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.Nature communications · 2023
   Article
6. From Crosstalk to Synergism: The Combined Effect of Cholesterol and PI(4,5)PAdvances in experimental medicine and biology · 2023
   Review
7. The versatile regulation of K2P channels by polyanionic lipids of the phosphoinositide and fatty acid metabolism.The Journal of general physiology · 2022
   Article
8. NMR studies of lipid regulation of the KBiochimica et biophysica acta. Biomembranes · 2021
   Article
9. Microorganisms · 2021
   Article
10. Microsecond-timescale simulations suggest 5-HT-mediated preactivation of the 5-HTProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
11. Loss of ACOT7 potentiates seizures and metabolic dysfunction.American journal of physiology. Endocrinology and metabolism · 2019
    Article
12. Molecular mechanism of phosphoinositides' specificity for the inwardly rectifying potassium channel Kir2.2.Chemical science · 2018
    Article
13. The Role of Lipid Interactions in Simulations of the α-Hemolysin Ion-Channel-Forming Toxin.Biophysical journal · 2018
    Article
14. Overview of the Microenvironment of Vasculature in Vascular Tone Regulation.International journal of molecular sciences · 2018
    Review
15. Modulation of the intrinsic neuronal excitability by multifunctional liposomes tailored for the treatment of Alzheimer's disease.International journal of nanomedicine · 2018
    Article
16. Phosphatidylinositol (4,5)-bisphosphate dynamically regulates the KScientific reports · 2017
    Article
17. Synaptotagmin-1 binds to PIP(2)-containing membrane but not to SNAREs at physiological ionic strength.Nature structural & molecular biology · 2015
    Article
18. Ion channel regulation by phosphoinositides analyzed with VSPs-PI(4,5)P2 affinity, phosphoinositide selectivity, and PI(4,5)P2 pool accessibility.Frontiers in pharmacology · 2015
    Article
19. Phosphoinositide control of membrane protein function: a frontier led by studies on ion channels.Annual review of physiology · 2015
    Review
20. Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel.Channels (Austin, Tex.) · 2015
    Article

Corrections and comments

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Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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