ArticleThe Journal of biological chemistry2008
Expression of the novel wheat gene TM20 confers enhanced cadmium tolerance to bakers' yeast.
Article in The Journal of biological chemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- A Genome-Wide Identification and Expression Analysis of the Casparian Strip Membrane Domain Protein-like Gene Family inPlants (Basel, Switzerland) · 2023Article
- Cadmium Transport in Maize Root Segments Using a Classical Physiological Approach: Evidence of Influx Largely Exceeding Efflux in Subapical Regions.Plants (Basel, Switzerland) · 2023Article
- Identification of wheat (Triticum aestivum L.) genotypes for food safety on two different cadmium contaminated soils.Environmental science and pollution research international · 2020Article
- Modulation of Plant and Fungal Gene Expression Upon Cd Exposure and Symbiosis in Ericoid MycorrhizalFrontiers in microbiology · 2020Article
- Functional characterisation of two phytochelatin synthases in rice (Oryza sativa cv. Milyang 117) that respond to cadmium stress.Plant biology (Stuttgart, Germany) · 2019Article
- Overexpression of heat stress-responsive TaMBF1c, a wheat (Triticum aestivum L.) Multiprotein Bridging Factor, confers heat tolerance in both yeast and rice.Plant molecular biology · 2015Article
- Rice DEP1, encoding a highly cysteine-rich G protein γ subunit, confers cadmium tolerance on yeast cells and plants.Journal of experimental botany · 2013Article
- Orthologs of the class A4 heat shock transcription factor HsfA4a confer cadmium tolerance in wheat and rice.The Plant cell · 2009Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Cadmium causes the generation of reactive oxygen species, which in turn causes cell damage. We isolated a novel gene from a wheat root cDNA library, which conferred Cd(II)-specific tolerance when expressed in yeast (Saccharomyces cerevisiae). The gene, which we called TaTM20, for Triticum aestivum transmembrane 20, encodes a putative hydrophobic polypeptide of 889 amino acids, containing 20 transmembrane domains arranged as a 5-fold internal repeating unit of 4 transmembrane domains each. Expression of TaTM20 in yeast cells stimulated Cd(II) efflux resulting in a decrease in the content of yeast intracellular cadmium. TaTM20-induced Cd(II) tolerance was maintained in yeast even under conditions of reduced GSH. These results demonstrate that TaTM20 enhances Cd(II) tolerance in yeast through the stimulation of Cd(II) efflux from the cell, partially independent of GSH. Treatment of wheat seedlings with Cd(II) induced their expression of TaTM20, decreasing subsequent root Cd(II) accumulation and suggesting a possible role for TaTM20 in Cd(II) tolerance in wheat.
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