ReviewDevelopmental cell2008
Linking kinetochore-microtubule binding to the spindle checkpoint.
Review in Developmental cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 69 citations in OpenAlex.
- KIF2C is essential for meiosis and manchette dynamics in male mice.Frontiers in cell and developmental biology · 2025Article
- Stain-free enucleation of mouse and human oocytes with a 1033 nm femtosecond laser.Journal of biomedical optics · 2024Article
- P53 independent pathogenic mechanisms contribute to BubR1 microcephaly.Frontiers in cell and developmental biology · 2023Article
- Twist1 induces chromosomal instability (CIN) in colorectal cancer cells.Human molecular genetics · 2020Article
- Nearly complete deletion of BubR1 causes microcephaly through shortened mitosis and massive cell death.Human molecular genetics · 2019Article
- Novel ESCRT functions at kinetochores.Aging · 2018Article
- Cis-trimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells.Oncotarget · 2018Article
- The mitochondrial metabolic checkpoint and aging of hematopoietic stem cells.Current opinion in hematology · 2016Review
- Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2.Nature communications · 2016Article
- Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Chromosoma · 2015Review
- Antimitotic drugs in the treatment of cancer.Cancer chemotherapy and pharmacology · 2015Review
- Physical limits on kinesin-5-mediated chromosome congression in the smallest mitotic spindles.Molecular biology of the cell · 2015Article
- Nuf2 is required for chromosome segregation during mouse oocyte meiotic maturation.Cell cycle (Georgetown, Tex.) · 2015Article
- CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.The Journal of cell biology · 2014Article
- Coiled-coil networking shapes cell molecular machinery.Molecular biology of the cell · 2012Article
- Mammalian chromosomes contain cis-acting elements that control replication timing, mitotic condensation, and stability of entire chromosomes.BioEssays : news and reviews in molecular, cellular and developmental biology · 2012Review
- Kinase activity of fission yeast Mph1 is required for Mad2 and Mad3 to stably bind the anaphase promoting complex.Current biology : CB · 2012Article
- Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore.The Journal of cell biology · 2012Article
- Spindle assembly checkpoint: the third decade.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2011Review
- Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint.The EMBO journal · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The spindle checkpoint blocks cell-cycle progression until chromosomes are properly attached to the mitotic spindle. Popular models propose that checkpoint proteins associate with kinetochores to produce a "wait anaphase" signal that inhibits anaphase. Recent data suggest that a two-state switch results from using the same kinetochore proteins to bind microtubules and checkpoint proteins. At least eight protein kinases are implicated in spindle checkpoint signaling, arguing that a traditional signal transduction cascade is integral to spindle checkpoint signaling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.