ArticleEpilepsia2008
Seizure remission and relapse in adults with intractable epilepsy: a cohort study.
Article in Epilepsia, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- The scale for estimating prognosis of epilepsy to predict in patients with epilepsy: a 506-patient cohort study.BMC neurology · 2026Article
- Dynamic evolution of frontal-temporal network connectivity in temporal lobe epilepsy: A magnetoencephalography study.Human brain mapping · 2024Article
- N-methyl-D-aspartate receptor autoantibody levels in children with intractable and non-intractable epilepsy.Heliyon · 2024Article
- Revisiting the concept of drug-resistant epilepsy: A TASK1 report of the ILAE/AES Joint Translational Task Force.Epilepsia · 2023Article
- Article
- A Retrospective Analysis of the Long-Term Outcome of Drug-Resistant Epilepsy in Children Treated in Urban India.Child neurology open · 2018Article
- Neurostimulation as a promising epilepsy therapy.Epilepsia open · 2017Review
- Application of RNS in refractory epilepsy: Targeting insula.Epilepsia open · 2017Article
- Recent advances in epilepsy.Journal of neurology · 2017Review
- Seizing Control: From Current Treatments to Optogenetic Interventions in Epilepsy.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2017Article
- Article
- New Techniques and Progress in Epilepsy Surgery.Current neurology and neuroscience reports · 2016Review
- Managing drug-resistant epilepsy: challenges and solutions.Neuropsychiatric disease and treatment · 2016Review
- Epilepsy: Guidelines on vagus nerve stimulation for epilepsy.Nature reviews. Neurology · 2013Article
- Pharmacoresistance and the role of surgery in difficult to treat epilepsy.Nature reviews. Neurology · 2012Review
- Patterns of treatment response in newly diagnosed epilepsy.Neurology · 2012Article
- Do recurrent seizure-related head injuries affect seizures in people with epilepsy?Epilepsy & behavior : E&B · 2012Article
- Usefulness of corregistration and post-processing of MR and interictal SPECT images for localization of epileptogenic focus in children - preliminary report.Polish journal of radiology · 2011Article
- Prognosis of intractable epilepsy: is long-term seizure freedom possible with medical management?Current neurology and neuroscience reports · 2011Review
- Remission and relapse in a drug-resistant epilepsy population followed prospectively.Epilepsia · 2011Article
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7 authors.
Funding
Abstract
purposeTo investigate the cumulative probabilities of >or=12 month seizure remission and seizure relapse following remission, and to test the associations of clinical characteristics with these two study end points in a prevalence cohort of intractable adult epilepsy patients during medical management.
methodsA retrospective cohort study of intractable epilepsy patients seen in 2001 at a single center was conducted. Kaplan-Meier analysis was used to estimate the cumulative probabilities of seizure remission and subsequent seizure relapse. Cox proportional hazards models were used to estimate the association (1) between clinical factors and >or=12 month seizure remission and (2) between clinical factors and seizure relapse following remission.
resultsOne hundred eighty-seven subjects met the eligibility criteria for intractable epilepsy. The estimate of probability of remission was about 4% per year. Seizure remission was temporary for some individuals, as 5 out of 20 subjects with remission ultimately relapsed. No clinical factors predicted the likelihood of achieving >or=12 month seizure remission or subsequent seizure relapse. DISCUSSION: Some people with intractable epilepsy achieve >or=12 month seizure remission during medical treatment. Remission, however, is only temporary for some individuals. We were unable to identify clear predictors for remission.
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