ArticleEuropean journal of epidemiology2008
Alcohol consumption and risk of colorectal cancer: the Findrink study.
Article in European journal of epidemiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Meta-analyses of colorectal cancer risk factors.Cancer causes & control : CCC · 2013Pooled it
- Application of fecal immunochemical test in colorectal cancer screening: A community-based, cross-sectional study in average-risk individuals in Hainan.World journal of gastrointestinal oncology · 2024Article
- Inflammatory biomarker score and cancer: A population-based prospective cohort study.BMC cancer · 2016Article
- Type A behavior pattern is not a predictor of premature mortality.International journal of behavioral medicine · 2015Article
- Associations between polymorphisms in the SYK promoter and susceptibility to sporadic colorectal cancer in a Southern Han Chinese population - a short report.Cellular oncology (Dordrecht, Netherlands) · 2015Article
- A telematic tool to predict the risk of colorectal cancer in white men and women: ColoRectal Cancer Alert (CRCA).Journal of medical systems · 2012Article
- Alcohol intake and risk of colorectal cancer: results from the UK Dietary Cohort Consortium.British journal of cancer · 2010Article
- Can we identify genes for alcohol consumption in samples ascertained for heterogeneous purposes?Alcoholism, clinical and experimental research · 2009Article
- The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study.BMC medical genetics · 2009Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the association between alcohol consumption and colorectal cancer because previous studies have yielded conflicting results. As part of the Findrink study, data from the Kuopio Ischaemic Heart Disease (KIHD) Risk Factor Study were analysed. The KIHD study is a cohort of 2,682 men from Eastern Finland with no history of cancer at baseline. The men were grouped into five groups according to their weekly alcohol intake in grams. Association between alcohol and colorectal cancer was examined using Cox proportional hazard models. There were 59 cases of colorectal cancer during an average follow up of 16.7 years. Men within the highest quintile of alcohol consumption had a median weekly alcohol intake of 198.8 g. Age and examination year adjusted risk ratio of colorectal cancer among men within the highest quintile of alcohol consumption was 4.4 (95% CI: 1.6-11.9, P-value = 0.004). After adjusting for potential confounders, such as vegetable consumption, fibre intake, smoking, family history of cancer, socio-economic status, leisure time physical activity, men with the highest amount of alcohol consumption still had a 3.5-fold (95% CI: 1.2-9.9, P-value = 0.021) increased risk of colorectal cancer. Exclusion of men diagnosed with colorectal cancer during the first 2 years of follow up from the analyses did not alter the risk increase. In conclusion, this study gives further evidence of a positive association between alcohol consumption and the risk of colorectal cancer.
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