ArticleEuropean journal of pediatrics2009
Enema-induced severe hyperphosphatemia in children.
Article in European journal of pediatrics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Severe hyperphosphatemia after administration of sodium-phosphate containing laxatives in children: case series and systematic review of literature.Pediatric surgery international · 2012Pooled it
- The Risks of Phosphate Enemas in Toddlers: A Life-Threatening Unawareness.Children (Basel, Switzerland) · 2024Article
- A Comparison of the Efficacy of Enema Solutions in Pediatric Emergency Department Patients.The Journal of emergency medicine · 2019Article
- Ileus and Intra-Abdominal Hypertension due to Phosphate- Containing Enema.Indian journal of pediatrics · 2016Article
- Flow-through peritoneal dialysis in neonatal enema-induced hyperphosphatemia.Pediatric nephrology (Berlin, Germany) · 2010Article
- Bowel management for the treatment of pediatric fecal incontinence.Pediatric surgery international · 2009Review
- Re: Enema-induced severe hyperphosphatemia in children.European journal of pediatrics · 2009Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the case of a 13-year-old boy with Costello syndrome and chronic constipation who received phosphate-containing Fleet-pediatric enemas at regular intervals. The day before admission he was given four enemas for severe constipation. Within 24 h the boy had developed severe hyperphosphatemia (phosphate 17.75 mmol/L), hypertonic dehydration (sodium 171 mmol/L) and severe hypocalcemia (calcium 0.56 mmol/L). With early intervention and treatment, the child survived without sequelae. Osmotically acting hypertonic phosphate enemas may result in severe toxicity. Children with developmental delay often display bowel dysfunction and chronic constipation and are therefore high-risk patients. The accepted opinion-that these enemas are not absorbed and therefore systemically inactive-is not true. Physicians should be aware of the potentially lethal complications of this treatment, which is part of everyday clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.