Evidence map›Paper›PMID 18408464›Full record

ReviewCurrent opinion in gastroenterology2008

Cholangiocarcinoma: lessons from Thailand.

Banchob Sripa, Chawalit Pairojkul

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Current opinion in gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04611100 (Efficacy of Intraductal Radiofrequency Ablation in Combination With Metallic Biliary Stenting in Advanced Hilar Cholangiocarcinoma), which is not on this map. Cited by 249 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
249citing papers in PubMed, 4 pooled it
19.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04611100 nacompletednot on this mapstarted 2020, after this paper: background citation

Efficacy of Intraductal Radiofrequency Ablation in Combination With Metallic Biliary Stenting in Advanced Hilar Cholangiocarcinoma

TypeinterventionalSponsorDepartment of Medical Services Ministry of Public Health of ThailandRan2020 to 2021Enrolled70ConditionsHilar Cholangiocarcinoma, Biliary ObstructionArmsELRA endoluminal radiofrequency ablation electrode (Taewoong, Seoul, Korea)
3 · Its place in the literature

Who cites it

249 citing papers in PubMed, 4 syntheses or guidelines pooled it, 519 citations in OpenAlex.

  1. Postoperative adjuvant chemotherapy for resectable cholangiocarcinoma.The Cochrane database of systematic reviews · 2021
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  11. Impact of Community-Based Health Education and Sanitation Interventions onInternational journal of environmental research and public health · 2026
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  14. Review
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189 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Banchob SripaDepartment of Pathology, Faculty of Medicine, Thailand.
Chawalit Pairojkul
Khon Kaen University · TH

Funding

Pathogenesis of Liver Fluke Induced Cancer in ThailandU01AI065871 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI BRINDLEY, PAUL J · 2005 to 2009
$3.5M
NIAID NIH HHS 1UO1 AI065871NIAID NIH HHS U01 AI065871
6 · The paper itself

Abstract

purpose of reviewTo present the background of liver fluke-associated cholangiocarcinoma in Thailand focusing on recent epidemiological data and pathogenesis of this bile duct cancer. RECENT

findingsMore systematic tumor registration in Thailand nowadays uncovers new high-incidence areas that are confined to not only the northeastern part but also some provinces in northern Thailand. The link between the liver fluke, Opisthorchis viverrini, and cholangiocarcinoma, particularly in terms of cellular and molecular pathogenesis, is further elucidated. SUMMARY: Thailand is still the country with the highest incidence of cholangiocarcinoma in the world. Liver fluke induces chronic inflammation leading to oxidative DNA damage of the infected biliary epithelium and malignant transformation. Eradication of the fluke and identification of high-risk populations are urgently needed.

Indexed as

AnimalsBile Duct NeoplasmsBile Ducts, IntrahepaticCholangiocarcinomaHumansLiver Diseases, ParasiticOpisthorchiasisThailand

Identifiers

PMID18408464
PMCPMC4130346
OpenAlexW1994216489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.