Evidence map›Paper›PMID 18407604›Full record

ArticleWorld journal of gastroenterology2008

Clinicopathologic characteristics of intrahepatic cholangiocarcinoma in patients with positive serum a-fetoprotein.

Yan-Ming Zhou, Jia-Mei Yang, Bin Li, Zheng-Feng Yin, Feng Xu, Bin Wang, Peng Liu, Zhi-Min Li

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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  17. Assessment of liver cancer biomarkers.Gastroenterology and hepatology from bed to bench · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Yan-Ming ZhouDepartment of Hepato-Biliary-Pancreato-Vascular Surgery, The First Xiamen Hospital, Fujian Medical University, Xiamen, China.
Jia-Mei Yang
Bin Li
Zheng-Feng Yin
Feng Xu
Bin Wang
Peng Liu
Zhi-Min Li
Second Military Medical University · CNEastern Hepatobiliary Surgery Hospital · CNFirst Affiliated Hospital of Xiamen University · CNMolecular Oncology (United States) · USOspedali Riuniti di Ancona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo explore clinicopathologic characteristics of intrahepatic cholangiocarcinoma (ICC) in patients with positive serum a-fetoprotein (AFP).

methodsOne hundred and thirty one patients who underwent surgical dissection for pathologically confirmed ICC were divided into a positive AFP (> 20 ng/mL) group (n = 32) and a negative AFP group (n = 99), whose clinicopathologic features were analyzed and compared.

resultsThe positive rate of HBsAg and liver cirrhosis of the positive AFP group was higher than that of the negative AFP group, while the positive rate of CA19-9 (> 37 U/mL) and the lymph node metastasis rate was lower.

conclusionICC patients with positive AFP share many clinicopathologic similarities with hepatocellular carcinoma.

Indexed as

AdultAgedalpha-FetoproteinsBile Duct NeoplasmsBile Ducts, IntrahepaticCholangiocarcinomaFemaleHepatitis B virusHumansLiverLiver CirrhosisLymphatic MetastasisMaleMiddle AgedStem Cellsalpha-Fetoproteins

Identifiers

PMID18407604
PMCPMC2703855
OpenAlexW2155043559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.