ArticleNucleic acids research1991
Isolation of the murine ribonuclease gene Rib-1: structure and tissue specific expression in pancreas and parotid gland.
Article in Nucleic acids research, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 13 citations in OpenAlex.
- Article
- Molecular cloning and characterization of a novel human ribonuclease (RNase k6): increasing diversity in the enlarging ribonuclease gene family.Nucleic acids research · 1996Article
- Sequences related to the ox pancreatic ribonuclease coding region in the genomic DNA of mammalian species.Journal of molecular evolution · 1993Article
- New nucleotide sequence data on the EMBL File Server.Nucleic acids research · 1992Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The mouse pancreatic ribonuclease gene Rib-1 was isolated from a library of mouse genomic DNA and sequenced. This small gene contains a nontranslated exon of 52 base pairs, an intron of 791 base pairs, and a coding exon of 741 base pairs. Rib-1 transcripts were detected in parotid gland as well as in pancreas. The abundance of the transcripts were approximately 200-fold greater in pancreatic RNA than in parotid RNA. The sites of transcription initiation were mapped by primer extension and ribonuclease protection assays. One major initiation site and several minor initiation sites were identified in pancreatic RNA. Transcription in parotid appears to be initiated from the same sites. Parotid-specific transcripts were not detected. The data suggest that Rib-1 is transcribed in pancreas and parotid from the same promoter. This is in contrast with the mechanism for production of amylase in pancreas and parotid, which is accomplished by tissue specific expression of different gene copies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.