ArticlePurinergic signalling2004
Immunolocalisation of P2Y receptors in the rat eye.
Article in Purinergic signalling, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Symptomatic intraocular pressure dysregulation during clopidogrel exposure after patent foramen ovale closure in a patient with ocular hypertension and angle crowding: a Case Report.Frontiers in medicine · 2026Article
- Rodent Models of Glaucoma: How Mice and Rats Can Help Human Vision Move Out of the Woods and Into the Light.Cells · 2025Review
- P2YInternational journal of molecular sciences · 2025Review
- Targeting purinergic receptors to attenuate inflammation of dry eye.Purinergic signalling · 2023Review
- Efficacy of Artificial Tears Based on an Extract ofInternational journal of molecular sciences · 2021Article
- Article
- Diadenosine tetraphosphate as a potential therapeutic nucleotide to treat glaucoma.Purinergic signalling · 2017Article
- Changes in P2Y Purinergic Receptor Expression in the Ciliary Body in a Murine Model of Glaucoma.Frontiers in pharmacology · 2017Article
- Ocular Purine Receptors as Drug Targets in the Eye.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2016Review
- Diadenosine tetraphosphate contributes to carbachol-induced tear secretion.Purinergic signalling · 2015Article
- Increased levels of extracellular ATP in glaucomatous retinas: Possible role of the vesicular nucleotide transporter during the development of the pathology.Molecular vision · 2015Article
- Purinergic receptors in ocular inflammation.Mediators of inflammation · 2014Review
- Silencing of P2Y(2) receptors reduces intraocular pressure in New Zealand rabbits.British journal of pharmacology · 2012Article
- Editorial.Purinergic signalling · 2011Article
- Activation of P2X receptors induces apoptosis in human retinal pigment epithelium.Investigative ophthalmology & visual science · 2011Article
- 2-MeS-beta,gamma-CCl2-ATP is a potent agent for reducing intraocular pressure.Journal of medicinal chemistry · 2010Article
- Silencing of P2Y2 receptor delays Ap4A-corneal re-epithelialization process.Molecular vision · 2009Article
- The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance.Purinergic signalling · 2009Article
- The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance.Purinergic signalling · 2008Article
- Topical application of nucleotides increase lysozyme levels in tears.Clinical ophthalmology (Auckland, N.Z.) · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nucleotides present an important role in ocular physiology which has been demonstrated by recent works that indicate their involvement in many ocular processes. P2Y are important among P2 receptors since they can control tear production, corneal wound healing, aqueous humour dynamics and retinal physiology. Commercial antibodies have allowed us to investigate the distribution of P2Y receptors in the cornea, anterior and posterior chamber of the eye and retina. The P2Y(1) receptor was present mainly in cornea, ciliary processes, and trabecular meshwork. The P2Y(2) receptors were present in cornea, ciliary processes and retinal pigmented epithelium. P2Y(4) was present in cornea, ciliary processes, photoreceptors, outer plexiform layer and ganglion cell layer. The P2Y(6) presented almost an identical distribution as the P2Y(4) receptor. The P2Y(11) was also detectable in the retinal pigmented epithelium. The detailed distribution of the receptors clearly supports the recent findings indicating the relevant role of nucleotides in the ocular function.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.