Evidence map›Paper›PMID 18404269›Full record

ArticleEuropean radiology2008

Carotid artery wall thickness and ischemic symptoms: evaluation using multi-detector-row CT angiography.

Luca Saba, Roberto Sanfilippo, Luigi Pascalis, Roberto Montisci, Giancarlo Caddeo, Giorgio Mallarini

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European radiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. CT imaging features of carotid artery plaque vulnerability.Annals of translational medicine · 2020
    Review
  6. Article
  7. Article
  8. Article
  9. CT Attenuation Analysis of Carotid Intraplaque Hemorrhage.AJNR. American journal of neuroradiology · 2018
    Article
  10. Carotid Doppler ultrasound evaluation in patients with pulsatile tinnitus.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2015
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Luca SabaDepartment of Radiology, Azienda Ospedaliero Universitaria Polo di Monserrato, s.s. 554 Monserrato, Cagliari, 09045, Italy. lucasaba@tiscali.it
Roberto Sanfilippo
Luigi Pascalis
Roberto Montisci
Giancarlo Caddeo
Giorgio Mallarini
Azienda Ospedaliero-Universitaria Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to determine if carotid artery wall thickness (CAWT) studied by using multi-detector-row CT angiography (MDCTA) can be considered an effective parameter predictive of increased risk of stroke. A total of 217 patients were retrospectively studied by using MDCTA. In all patients CAWT was measured with an internal digital caliper. Continuous data were described as the mean value +/- standard deviation (SD), and they were compared with Student's t-test. Scatter plots to determine interobserver agreement were performed, and correlation coefficient was calculated with Pearson statistics. A P value <0.05 was considered to mean statistical significance. Measurements of the distal common CAWT ranged from 0.5 to 1.6 mm. In the patient group without stroke, average CAWT was 0.82 mm (0.22 SD), whereas in patient group with stroke it was 1.096 mm (0.21 SD). CAWT in patients without stroke showed statistical difference (P < 0.0001) when compared to patients with stroke. By using a threshold of 1 mm, an important statistical association between thick CAWT and stroke was found (P < 0.0001). In fact, patients with > or = 1 mm CAWT had stroke with an odds ratio of 8.16 when compared with patients with <1 mm CAWT. Resulting data suggested that an increased CAWT is an indicator for risk of stroke. This parameter should be considered in addition to other well-known risk factors such as diabetes, hypertension, smoking, and dyslipidemia.

Indexed as

AdultAgedAged, 80 and overBrain IschemiaCarotid ArteriesCerebral AngiographyFemaleHumansItalyMaleMiddle AgedRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsRisk AssessmentRisk FactorsSensitivity and Specificity

Identifiers

PMID18404269
OpenAlexW2091547670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.