Evidence map›Paper›PMID 18402251›Full record

ArticleWorld journal of pediatrics : WJP2008

Is pneumoperitoneum an absolute indication for surgery in necrotizing enterocolitis?

Vijai D Upadhyaya, A N Gangopadhyay, Anand Pandey, Ashish Upadhyaya, T Vittal Mohan, S C Gopal, D K Gupta

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in World journal of pediatrics : WJP, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Vijai D UpadhyayaDepartment of Pediatric Surgery, IMS, BHU, Varanasi, India. upadhyayavj@rediffmail.com
A N Gangopadhyay
Anand Pandey
Ashish Upadhyaya
T Vittal Mohan
S C Gopal
D K Gupta
Institute of Medical Sciences · INBanaras Hindu University · INIndian Institute of Technology BHU · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNecrotizing enterocolitis (NEC) is the most common gastrointestinal medical/surgical emergency in neonates. Non-operative support is needed in 70% of NEC cases, and surgical intervention in the rest 30%. Historically, pneumoperitoneum has been considered as an absolute indication for laparotomy. In the present study we emphasize that pneumoperitoneum is not an absolute indication for exploratory laparotomy in NEC cases.

methodsWe prospectively studied 58 patients with severe NEC having pneumoperitoneum on abdominal X-ray in the last 5 years. At the time of admission, the patients were given intravenous fluid, total parental nutrition, blood transfusion and broad spectrum antibiotics followed by abdominal tapping (paracentesis). All the patients with pneumoperitoneum were closely monitored for 48 hours if abdominal tapping was repeated. When the disease seemed to worsen clinically, radiologically and laboratorially, the patient was subjected to exploratory laparotomy.

resultsOf the 58 patients, 40 were treated conservatively whereas 18 underwent surgical intervention. The overall mortality in the present study was 12.1%, including 5% of the patients managed conservatively and 27% of the patients undergoing surgery.

conclusionsPneumoperitoneum is not an absolute indication for surgery in cases of neonatal NEC. Most of the patients can be treated conservatively.

Indexed as

Digestive System Surgical ProceduresEnterocolitis, NecrotizingFemaleHumansInfant, NewbornInfant, Newborn, DiseasesInfant, PrematureMaleParacentesisPneumoperitoneumProspective StudiesTreatment Outcome

Identifiers

PMID18402251
OpenAlexW2156153942

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.