ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2008
Craniocervical developmental anatomy and its implications.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.
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Who cites it
80 citing papers in PubMed, 1 synthesis or guideline pooled it, 237 citations in OpenAlex.
- Natural history and management of cervical spine disease in chondrodysplasia punctata and coumarin embryopathy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Pooled it
- Trial
- Clival Screw Placement in Patient with atlas assimilation: A CT-based feasibility study.Scientific reports · 2016Trial
- Unfused transverse foramen of the atlas vertebra in the Neandertal lineage fossils.Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- The mutational burden in os odontoideum patients.Orphanet journal of rare diseases · 2026Article
- Tailored vertebral artery mobilisation in complex craniovertebral junction surgery.Neurosurgical review · 2026Observational
- MRI-based Quantification of Ossification Centers in the Human Fetal Atlas and Axis Vertebrae.Current medical imaging · 2026Article
- Chiari Malformation and Hindbrain Descent: Characterization and New Classification Based on Mechanism and Pathogenesis, and Surgical Management.Neurospine · 2025Article
- Sagittal changes in the dens significantly slowed after 12 years of age.Brain & spine · 2025Article
- Morphometric study of the atlantooccipital and the lateral atlantoaxial joints in small breed dogs with and without atlantoaxial instability.Frontiers in veterinary science · 2025Article
- Treatment of a symptomatic patient with severe progressive odontoid invagination and Cervicothoracic scoliosis: A case report.Clinical case reports · 2024Article
- Biomechanical Study of Atlanto-occipital Instability in Type II Basilar Invagination: A Finite Element Analysis.Neurospine · 2024Article
- Osseous bridging of the condylar fossa: report of a rare anatomical variation at the outer skull base.Surgical and radiologic anatomy : SRA · 2024Article
- The role of occipital condyle and atlas anomalies on occipital cervical fusion outcomes in Chiari malformation type I with syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium.Journal of neurosurgery. Pediatrics · 2024Article
- A new etiology of nontraumatic C0-C1-C2-Complex instability - abnormality of musculus rectus capitis posterior minor: a case report.Archives of orthopaedic and trauma surgery · 2024Article
- Os odontoideum and craniovertebral junction instability secondary to dystonia: case series and review of the literature.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Review
- Article
- Database Review of 514 Patients with Os Odontoideum. Detailed Analysis of 258 Surgically Treated (1978-2019).Advances and technical standards in neurosurgery · 2024Article
- Ponticulus posticus and skeletal malocclusion: A pilot study in a Southern Italian pre-orthodontic court.Open medicine (Warsaw, Poland) · 2024Article
- Congenital atlanto-occipital dislocation in a patient with Down syndrome: a case report.Skeletal radiology · 2023Article
20 more citing papers are in PubMed but not listed here.
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCongenital and developmental osseous abnormalities and anomalies that affect the craniocervical junction complex can result in neural compression and vascular compromise and can manifest itself with abnormal cerebrospinal fluid dynamics. An understanding of the development of the craniocervical junction is essential to recognize the pathological abnormalities. MATERIALS AND
methodsAtlas assimilation, segmentation failures, os odontoideum, basilar invagination, and the various syndromes that affect the craniocervical junction have been analyzed. The natural history provides an added insight into its treatment.
resultsProatlas segmentation abnormalities surrounded the foramen magnum and the posterior arch of C1. Hindbrain herniation was associated in 33 of the 90 children involved. Spastic quadriparesis presented in 80% and lower cranial nerve abnormalities in 33%. Vertebrobasilar dysfunction was observed in 40% and trauma presentation seen in 60% of individuals. Atlas assimilation was present in 550 individuals who were evaluated for craniovertebral junction abnormalities. Hindbrain herniation occurred in 38%. Segmentation failure of C2 and C3 vertebrae compounded the abnormal dynamics resulting in atlantoaxial instability. This was a reducible instability with formation of pannus around the odontoid process until it became irreducible at approximately 14 years of age. Unilateral atlas assimilation caused torticollis in children. Os odontoideum was investigated regarding craniocervical trauma at a young age.
conclusionThe conclusion was that os odontoideum was associated with an unrecognized fracture in children below the age of 5 with a previously normal odontoid structure as observed in our series. Atlas and axis abnormalities were reviewed in this series. This large database has provided an understanding of the natural history of many entities and allowed treatment protocols to be established that have stood the test of time.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.