Evidence map›Paper›PMID 18401223›Full record

Trial reportJournal of clinical hypertension (Greenwich, Conn.)2008

A cluster randomized trial to evaluate physician/pharmacist collaboration to improve blood pressure control.

Barry L Carter, George R Bergus, Jeffrey D Dawson, Karen B Farris, William R Doucette, Elizabeth A Chrischilles, Arthur J Hartz

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00201045 (Collaborative Management of Hypertension), which is not on this map. Cited by 103 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 17 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00201045 nacompletednot on this map

Collaborative Management of Hypertension

TypeinterventionalSponsorUniversity of IowaRan2003 to 2006Enrolled179ConditionsHypertensionArmsPhysician/Pharmacist Collaborative Teams
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 17 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Impact of patient care teams on blood pressure control in patients with hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Pooled it
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  6. A Systematic Review of Network Studies Based on Administrative Health Data.International journal of environmental research and public health · 2020
    Pooled it
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  8. Pharmacist services for non-hospitalised patients.The Cochrane database of systematic reviews · 2018
    Pooled it
  9. Patient and public perspectives of community pharmacies in the United Kingdom: A systematic review.Health expectations : an international journal of public participation in health care and health policy · 2018
    Pooled it
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  18. Trial
  19. RBMJ open · 2021
    Trial
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Barry L CarterDivision of Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA. barry.carter@uiowa.edu
George R Bergus
Jeffrey D Dawson
Karen B Farris
William R Doucette
Elizabeth A Chrischilles
Arthur J Hartz

Funding

Collaborative Management of HypertensionR01HL069801 · NHLBI · UNIVERSITY OF IOWA · PI CARTER, BARRY L · 2003 to 2005
$2.0M
NHLBI NIH HHS HL 069801NHLBI NIH HHS R01 HL069801
6 · The paper itself

Abstract

This was a prospective, cluster randomized controlled trial in patients with uncontrolled hypertension aged 21 to 85 years (mean, 61 years). Pharmacists made recommendations to physicians for patients in the intervention clinics (n=101) but not patients in the control clinics (n=78). The mean adjusted difference in systolic blood pressure (BP) between the control and intervention groups was 8.7 mm Hg (95% confidence interval [CI], 4.4-12.9), while the difference in diastolic BP was 5.4 mm Hg (CI, 2.8-8.0) at 9 months. The 24-hour BP levels showed similar effects, with a mean systolic BP level that was 8.8 mm Hg lower (CI, 5.0-12.6) and a mean diastolic BP level that was 4.6 mm Hg (CI, 2.4-6.8) lower in the intervention group. BP was controlled in 89.1% of patients in the intervention group and 52.9% in the control group (adjusted odds ratio, 8.9; CI, 3.8-20.7; P<.001). Physician/pharmacist collaboration achieved significantly better mean BP values and overall BP control rates, primarily by intensification of medication therapy and improving patient adherence.

Indexed as

Interprofessional RelationsPatient Care TeamPharmacistsPhysiciansAdultAgedAged, 80 and overBlood PressureCluster AnalysisCooperative BehaviorEducational MeasurementFemaleHumansHypertensionMaleMiddle Aged

Identifiers

PMID18401223
PMCPMC2453045

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.