Evidence map›Paper›PMID 18398312›Full record

ArticleEpigenetics

WAMIDEX: a web atlas of murine genomic imprinting and differential expression.

Reiner Schulz, Kathryn Woodfine, Trevelyan R Menheniott, Deborah Bourc'his, Timothy Bestor, Rebecca J Oakey

Open access · hybridAbstract read
In one paragraph

Article in Epigenetics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
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  3. The imprintedeLife · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Reiner SchulzDepartment of Medical & Molecular Genetics, School of Medicine at Guy's, King's College & St Thomas' Hospitals, King's College London, London, United Kingdom. reiner.schulz@genetics.kcl.ac.uk
Kathryn Woodfine
Trevelyan R Menheniott
Deborah Bourc'his
Timothy Bestor
Rebecca J Oakey
St Thomas' Hospital · GBColumbia University · USInserm · FRKing's College Hospital · GBKing's College School · GB

Funding

Biotechnology and Biological Sciences Research CouncilWellcome Trust 071002
6 · The paper itself

Abstract

The mouse is an established model organism for the study of genomic imprinting. Mice with genetic material originating from only one parent (e.g., mice with uniparental chromosomal duplications) or gene mutations leading to epigenetic deficiencies have proven to be particularly useful tools. In the process of our studies we have accumulated a large set of expression microarray measurements in samples derived from these types of mice. Here, we present the collation of these and third-party microarray data that are relevant to genomic imprinting into a Web Atlas of Murine genomic Imprinting and Differential EXpression (WAMIDEX: https://atlas.genetics.kcl.ac.uk). WAMIDEX integrates the most comprehensive literature-derived catalog of murine imprinted genes to date with a genome browser that makes the microarray data immediately accessible in annotation-rich genomic context. In addition, WAMIDEX exemplifies the use of the self-organizing map method for the discovery of novel imprinted genes from microarray data. The parent-of-origin-specific expression of imprinted genes is frequently limited to specific tissues or developmental stages, a fact that the atlas reflects in its design and data content.

Indexed as

Databases, Nucleic AcidGene Expression ProfilingGenomic ImprintingAnimalsGenomeMiceOligonucleotide Array Sequence Analysis

Identifiers

PMID18398312
PMCPMC2492384
OpenAlexW2042674727

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.