Evidence map›Paper›PMID 18398285›Full record

ArticleAnnals of Saudi medicine

Increased bone mineral density in postmenopausal women with type 2 diabetes mellitus.

Irzal Hadzibegovic, Blazenka Miskic, Vesna Cosic, Deiti Prvulovic, Dragica Bistrovic

Abstract read
In one paragraph

Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Bone health and type 2 diabetes mellitus: a systematic review.Physiotherapy Canada. Physiotherapie Canada · 2011
    Pooled it
  3. Article
  4. Assessment of bone quality in patients with diabetes mellitus.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Bone Mineral Density of the Radius Predicts All-Cause Mortality in Patients With Type 2 Diabetes: Diabetes Heart Study.Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Irzal HadzibegovicDepartment of Internal Medicine, General Hospital, Dr Josip Bencevic, Slavonski Brod, Croatia. irzal@vip.hr
Blazenka Miskic
Vesna Cosic
Deiti Prvulovic
Dragica Bistrovic

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesStudies of bone mineral density (BMD) in women with type 2 diabetes mellitus have shown conflicting results. We conducted this study to determine whether postmenopausal women with diabetes have higher BMD than non-diabetic women of similar age, and to investigate the relationship between BMD and relevant clinical characteristics in these groups of women. PATIENTS AND

methodsWe retrospectively analyzed lumbar spine, femoral neck, and radius BMD data and other relevant clinical data for 130 postmenopausal women with type 2 diabetes mellitus and 166 non-diabetic women collected during a voluntary screening for osteoporosis in postmenopausal women without a history of low bone mass or osteoporotic fractures.

resultsWomen with type 2 diabetes mellitus had significantly higher mean lumbar spine BMD ( 0.903+/-0.165 vs. 0.824+/-0.199, respectively, P<.001) and mean femoral neck BMD (0.870+/-0.132 vs. 0.832+/-0.134, respectively, P<.05) than non-diabetic women. In both groups of women, age correlated negatively with BMD levels at all three anatomical sites. Higher body mass index was associated only with higher lumbar spine BMD in both groups. Alkaline phosphatase levels showed a negative correlation with BMD at all sites in women with type 2 diabetes mellitus.

conclusionPostmenopausal women with type 2 diabetes mellitus have higher BMD levels than non-diabetic women with similar clinical characteristics, and require a more scrutinized approach in managing low bone mass.

Indexed as

Bone DensityPostmenopauseAbsorptiometry, PhotonAdultAgedAged, 80 and overAge FactorsAlkaline PhosphataseBody Mass IndexDiabetes Mellitus, Type 2FemaleFemur NeckHumansLumbar VertebraeMiddle AgedRadiusAlkaline Phosphatase

Identifiers

PMID18398285
PMCPMC6074519

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.