Evidence map›Paper›PMID 18396115›Full record

ArticleDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver2008

Natural history of Helicobacter pylori infection.

P Correa, M B Piazuelo

Abstract read
In one paragraph

Article in Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
9.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 164 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The cost-effectiveness of sequential versus standard triple therapy forSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Trial
  4. Prevalence of Helicobacter pylori Infection in Geriatric Adults: A Single-Center Cohort Study from Türkiye.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026
    Article
  5. Review
  6. Article
  7. A critical review onFrontiers in cellular and infection microbiology · 2025
    Review
  8. Molecular Mechanisms of Biofilm Formation inAntibiotics (Basel, Switzerland) · 2024
    Review
  9. Cancers · 2024
    Article
  10. Article
  11. Article
  12. Diagnostic and therapeutic recommendations onPrzeglad gastroenterologiczny · 2023
    Article
  13. A Predictive Model of Noncardia Gastric Adenocarcinoma Risk Using Antibody Response to Helicobacter pylori Proteins and Pepsinogen.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  14. Raman Spectroscopy: A Novel Technology for Gastric Cancer Diagnosis.Frontiers in bioengineering and biotechnology · 2022
    Review
  15. Pathogens (Basel, Switzerland) · 2021
    Review
  16. International journal of environmental research and public health · 2021
    Article
  17. Article
  18. Rejuvenation ofFrontiers in pharmacology · 2021
    Article
  19. Article
  20. Changes in Seroprevalence ofJournal of Korean medical science · 2020
    Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

P CorreaDivision of Gastroenterology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. pelayo.correa@vanderbilt.edu
M B Piazuelo
Vanderbilt University Medical Center · US

Funding

Project 3 - Molecular Signatures of Gastric Carcinogenesis in the Host Response to H. pyloriP01CA028842 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILSON, KEITH T. · 1985 to 2019
$15.8M
NCI NIH HHS P01 CA028842NCI NIH HHS P01CA028842
6 · The paper itself

Abstract

This report describes the modalities of chronic gastritis induced by Helicobacter pylori infection in different populations. The full gamut of lesions representing the precancerous cascade is very prevalent in populations of low socioeconomic background experiencing very high gastric cancer risk, as seen in the Latin American Andes Mountains. In populations of high socioeconomic standards and high cancer risk, such as Japan and Korea, the precancerous cascade predominates and "early" cancers are also diagnosed frequently. Some reports describe frequent corpus atrophy, not prominent in the former group. The so-called African enigma is seen in populations of low socioeconomic standards, usually living at low altitudes, with high prevalence of infection but low frequency of cancer and precancerous lesions. In populations in transition from high to low cancer risk, duodenal ulcer and antral non-atrophic gastritis are frequently seen. In affluent societies at low risk of cancer, such as Western Europe, Australia and North America, mild non-atrophic gastritis associated with low virulence Helicobacter pylori genotypes predominate. The varied phenotypes of gastritis may reflect secular changes in the ecology of our species.

Indexed as

Helicobacter pyloriChronic DiseaseEuropeGastritis, AtrophicHelicobacter InfectionsHumansItalyJapanKoreaLatin AmericaNorth AmericaPrecancerous ConditionsPrevalenceRisk FactorsSocioeconomic FactorsStomach Neoplasms

Identifiers

PMID18396115
PMCPMC3142999
OpenAlexW2145957203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.