ReviewNeurotoxicology2008
Immunologic and neurodevelopmental susceptibilities of autism.
Review in Neurotoxicology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Environmental toxicants and autism spectrum disorders: a systematic review.Translational psychiatry · 2014Pooled it
- Parental occupational exposure to solvents and autism spectrum disorder: An exploratory look at gene-environment interactions.Environmental research · 2023Article
- Inhibition of Trpv4 rescues circuit and social deficits unmasked by acute inflammatory response in a Shank3 mouse model of Autism.Molecular psychiatry · 2022Article
- Early Transcriptomic Changes upon Thalidomide Exposure Influence the Later Neuronal Development in Human Embryonic Stem Cell-Derived Spheres.International journal of molecular sciences · 2020Article
- Oxidative Stress Challenge Uncovers Trichloroacetaldehyde Hydrate-Induced Mitoplasticity in Autistic and Control Lymphoblastoid Cell Lines.Scientific reports · 2017Article
- Immune Contributions to Cause and Effect in Autism Spectrum Disorder.Biological psychiatry · 2017Article
- Immune mediators in the brain and peripheral tissues in autism spectrum disorder.Nature reviews. Neuroscience · 2015Review
- Bisphenol A Exposure in Children With Autism Spectrum Disorders.Autism research : official journal of the International Society for Autism Research · 2015Article
- Prenatal exposure to a common organophosphate insecticide delays motor development in a mouse model of idiopathic autism.PloS one · 2015Article
- Organic Compounds Detected in Deciduous Teeth: A Replication Study from Children with Autism in Two Samples.Journal of environmental and public health · 2015Article
- Genetic aspects of autism spectrum disorders: insights from animal models.Frontiers in cellular neuroscience · 2014Review
- Potential Role of Selenoenzymes and Antioxidant Metabolism in relation to Autism Etiology and Pathology.Autism research and treatment · 2014Review
- Uncovering the etiology of autism spectrum disorders: genomics, bioinformatics, environment, data collection and exploration, and future possibilities.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2014Article
- Autism and phthalate metabolite glucuronidation.Journal of autism and developmental disorders · 2013Article
- The pathophysiology of autism.Global advances in health and medicine · 2013Review
- Exposure to lipophilic chemicals as a cause of neurological impairments, neurodevelopmental disorders and neurodegenerative diseases.Interdisciplinary toxicology · 2013Review
- Parental occupational exposures and autism spectrum disorder.Journal of autism and developmental disorders · 2012Article
- Modeling autism: a systems biology approach.Journal of clinical bioinformatics · 2012Article
- Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53.PloS one · 2012Article
- Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J mice.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
Symposium 5 focused on research approaches that are aimed at understanding common patterns of immunological and neurological dysfunction contributing to neurodevelopmental disorders such as autism and ADHD. The session focused on genetic, epigenetic, and environmental factors that might act in concert to influence autism risk, severity and co-morbidities, and immunological and neurobiological targets as etiologic contributors. The immune system of children at risk of autism may be therefore especially susceptible to psychological stressors, exposure to chemical triggers, and infectious agents. Identifying early biomarkers of risk provides tangible approaches toward designing studies in animals and humans that yield a better understanding of environmental risk factors, and can help identify rational intervention strategies to mitigate these risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.