Evidence map›Paper›PMID 18394275›Full record

ArticleEmerging infectious diseases2008

Beta-herpesviruses in febrile children with cancer.

Stephanie Yee-Guardino, Kate Gowans, Belinda Yen-Lieberman, Pamela Berk, Debra Kohn, Fu-Zhang Wang, Lara Danziger-Isakov, Camille Sabella, Sarah Worley, Philip E Pellett and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Infections in the immunocompromised.Advances in experimental medicine and biology · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Stephanie Yee-GuardinoCleveland Clinic Children's Hospital, Cleveland, OH, USA.
Kate Gowans
Belinda Yen-Lieberman
Pamela Berk
Debra Kohn
Fu-Zhang Wang
Lara Danziger-Isakov
Camille Sabella
Sarah Worley
Philip E Pellett
Johanna Goldfarb
Cleveland Clinic · USUniversity School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a cross-sectional study of beta-herpesviruses in febrile pediatric oncology patients (n = 30), with a reference group of febrile pediatric solid-organ transplant recipients (n = 9). One (3.3%) of 30 cancer patients and 3 (33%) of 9 organ recipients were PCR positive for cytomegalovirus. Four (13%) of 30 cancer patients and 3 (33%) of 9 transplant recipients had human herpesvirus 6B (HHV-6B) DNAemia, which was more common within 6 months of initiation of immune suppression (4 of 16 vs. 0 of 14 cancer patients; p = 0.050). HHV-6A and HHV-7 were not detected. No other cause was identified in children with HHV-6B or cytomegalovirus DNAemia. One HHV-6B-positive cancer patient had febrile disease with concomitant hepatitis. Other HHV-6B-positive children had mild "viral" illnesses, as did a child with primary cytomegalovirus infection. Cytomegalovirus and HHV-6B should be included in the differential diagnosis of febrile disease in children with cancer.

Indexed as

Immunocompromised HostAdolescentAdultBetaherpesvirinaeChildChild, PreschoolCross-Sectional StudiesFemaleHerpesviridae InfectionsHumansInfantMaleNeoplasmsOrgan TransplantationViremia

Identifiers

PMID18394275
PMCPMC11323659
OpenAlexW2125340537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.