Evidence map›Paper›PMID 18394273›Full record

ReviewEmerging infectious diseases2008

Emericella quadrilineata as cause of invasive aspergillosis.

Paul E Verweij, János Varga, Jos Houbraken, Antonius J M M Rijs, Frans M Verduynlunel, Nicole M A Blijlevens, Yvonne R Shea, Steven M Holland, Adilia Warris, Willem J G Melchers and 1 more

Open access · diamondAbstract readCase ReportsReview
In one paragraph

Review in Emerging infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Accelerating the understanding ofCurrent research in microbial sciences · 2024
    Review
  3. Review
  4. Four New Species ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Article
  7. The Emergence of Rare ClinicalFrontiers in microbiology · 2019
    Article
  8. EmergingOpen forum infectious diseases · 2018
    Review
  9. Article
  10. Studies in mycology · 2016
    Article
  11. Aspergillosis in Chronic Granulomatous Disease.Journal of fungi (Basel, Switzerland) · 2016
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Paul E VerweijRadboud University Nijmegen Medical Center, Nijmegen, the Netherlands. p.verweij@mmb.umcn.nl
János Varga
Jos Houbraken
Antonius J M M Rijs
Frans M Verduynlunel
Nicole M A Blijlevens
Yvonne R Shea
Steven M Holland
Adilia Warris
Willem J G Melchers
Robert A Samson
Radboud University Nijmegen · NLNational Institutes of Health · USWesterdijk Fungal Biodiversity Institute · NLUniversity of Szeged · HU

Funding

Transgenic Animal Models Of Human Immune DefectsZIAAI000646 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI HOLLAND, STEVEN · 2009 to 2025
$22.2M
TRANSGENIC ANIMAL MODELS OF HUMAN IMMUNE DEFECTSZ01AI000646 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI HOLLAND, STEVEN M · 1992 to 2008
$2.4M
6 · The paper itself

Abstract

We noted a cluster of 4 cases of infection or colonization by Emericella spp., identified by sequence-based analysis as E. quadrilineata. Sequence-based analysis of an international collection of 33 Emericella isolates identified 12 as E. nidulans, all 12 of which had previously been identified by morphologic methods as E. nidulans. For 12 isolates classified as E. quadrilineata, only 6 had been previously identified accordingly. E. nidulans was less susceptible than E. quadrilineata to amphotericin B (median MICs 2.5 and 0.5 mg/L, respectively, p<0.05); E. quadrilineata was less susceptible than E. nidulans to caspofungin (median MICs, 1.83 and 0.32 mg/L, respectively, p<0.05). These data indicate that sequence-based identification is more accurate than morphologic examination for identifying Emericella spp. and that correct species demarcation and in vitro susceptibility testing may affect patient management.

Indexed as

AdultAntifungal AgentsAspergillosisBase CompositionChildDNA, FungalDNA, IntergenicEmericellaFemaleHumansMaleMiddle AgedMycosesPhylogenyAntifungal AgentsDNA, FungalDNA, Intergenic

Identifiers

PMID18394273
PMCPMC2570940
OpenAlexW2122295152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.