ReviewStem cells and development2008
Epigenetic regulation of mammalian stem cells.
Review in Stem cells and development, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 83 citations in OpenAlex.
- Neural stem cell-derived extracellular vesicles: mini players with key roles in neurogenesis, immunomodulation, neuroprotection and aging.Frontiers in molecular biosciences · 2023Review
- SHANK family on stem cell fate and development.Cell death & disease · 2022Review
- AlClWorld journal of stem cells · 2020Article
- The Synthetic Cannabinoids THJ-2201 and 5F-PB22 Enhance In Vitro CBInternational journal of molecular sciences · 2020Article
- Histone acetylation and the role of histone deacetylases in normal cyclic endometrium.Reproductive biology and endocrinology : RB&E · 2020Review
- Prediction model construction of mouse stem cell pluripotency using CpG and non-CpG DNA methylation markers.BMC bioinformatics · 2020Article
- Neural stem cells: developmental mechanisms and disease modeling.Cell and tissue research · 2018Article
- miR-124 promotes proliferation and differentiation of neuronal stem cells through inactivating Notch pathway.Cell & bioscience · 2017Article
- Epigenetic Modulation of Stem Cells in Neurodevelopment: The Role of Methylation and Acetylation.Frontiers in cellular neuroscience · 2017Review
- An epigenetic view of developmental diseases: new targets, new therapies.World journal of pediatrics : WJP · 2016Review
- Preserved neurogenesis in non-demented individuals with AD neuropathology.Scientific reports · 2016Article
- Genetics and Epigenetics in Adult Neurogenesis.Cold Spring Harbor perspectives in biology · 2016Review
- Hepatoepigenetic Alterations in Viral and Nonviral-Induced Hepatocellular Carcinoma.BioMed research international · 2016Review
- 5-Hydroxymethylcytosine: A new player in brain disorders?Experimental neurology · 2015Review
- Concise review: Fragile X proteins in stem cell maintenance and differentiation.Stem cells (Dayton, Ohio) · 2014Review
- microRNAs: key triggers of neuronal cell fate.Frontiers in cellular neuroscience · 2014Review
- Neonatal tumours.Pediatric surgery international · 2013Review
- Epigenetic regulation in adult stem cells and cancers.Cell & bioscience · 2013Article
- Histone demethylase dUTX antagonizes JAK-STAT signaling to maintain proper gene expression and architecture of the Drosophila testis niche.Development (Cambridge, England) · 2013Article
- An epigenetic feedback regulatory loop involving microRNA-195 and MBD1 governs neural stem cell differentiation.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Two critical properties of stem cells are self-renewal and multipotency. The maintenance of their "stemness" state and commitment to differentiation are therefore tightly controlled by intricate molecular networks. Epigenetic mechanisms, including DNA methylation, chromatin remodeling and the noncoding RNA-mediated process, have profound regulatory roles in mammalian gene expression. Recent studies have shown that epigenetic regulators are key players in stem cell biology and their dysfunction can result in human diseases such as cancer and neurodevelopmental disorders. Here, we review the recent evidences that advance our knowledge in epigenetic regulations of mammalian stem cells, with focus on embryonic stem cells and neural stem cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.