ReviewWorld journal of urology2008
Risk stratification and prognostication of renal cell carcinoma.
Review in World journal of urology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 45 citations in OpenAlex.
- [Organ and kidney function preservation in renal cell carcinoma].Der Urologe. Ausg. A · 2014Trial
- Transient variations in the serum concentrations of cell adhesion molecules following retroperitoneal laparoscopic and open radical nephrectomy for localized renal-cell carcinoma.Journal of endourology · 2012Trial
- Prognostic value of D-lactate dehydrogenase in patients with clear cell renal cell carcinoma.Oncology letters · 2018Article
- SOX2 and SOX12 are predictive of prognosis in patients with clear cell renal cell carcinoma.Oncology letters · 2018Article
- Progression of Human Renal Cell Carcinoma via Inhibition of RhoA-ROCK Axis by PARG1.Translational oncology · 2017Article
- The rationale and the role of lymph node dissection in renal cell carcinoma.World journal of urology · 2017Review
- Primary Tumor Characteristics Are Important Prognostic Factors for Sorafenib-Treated Patients with Metastatic Renal Cell Carcinoma: A Retrospective Multicenter Study.BioMed research international · 2017Article
- ITGA2B and ITGA8 are predictive of prognosis in clear cell renal cell carcinoma patients.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Article
- Comparison of the prognostic value of pretreatment measurements of systemic inflammatory response in patients undergoing curative resection of clear cell renal cell carcinoma.World journal of urology · 2015Article
- Upregulation of COL6A1 is predictive of poor prognosis in clear cell renal cell carcinoma patients.Oncotarget · 2015Article
- Identification of high-risk patients with clear cell renal cell carcinoma based on interphase-FISH.British journal of cancer · 2014Article
- B7-H4 expression is elevated in human U251 glioma stem-like cells and is inducible in monocytes cultured with U251 stem-like cell conditioned medium.Chinese journal of cancer · 2013Article
- Early immune outcome of retroperitoneal laparoscopic radical nephrectomy for localized renal cell carcinoma: a prospective, randomized study.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2012Article
- Tyrosine kinase expression profile in clear cell renal cell carcinoma.World journal of urology · 2012Article
- Urinary collecting system invasion is no independent prognostic factor in renal cell carcinoma.World journal of urology · 2010Article
- Urinary collecting system invasion reflects adverse long-term outcome and is associated with simultaneous metastatic spread at the time of surgery and with multilocular dissemination during postsurgical follow-up in renal cell cancer.World journal of urology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo review the most recent data on prognostic factors and describe the characteristics and prognostic accuracy of the most important prognostic systems available to predict the risk of recurrence, progression, and mortality in patients with renal cell carcinoma (RCC).
methodsThe study was based on a non-systematic review of literature.
resultsClinical (performance status, and mode of presentation), anatomical (size and extension of the primary tumor, lymph node involvement, and distant metastasis), and histological factors (histological subtypes, nuclear grade, and tumor necrosis) are the most largely evaluated prognostic factors in RCC. Valuable prognostic accuracy has been shown for several laboratory parameters (erythrocyte sedimentation rate, platelet count, serum calcium, hemoglobin, and lactate dehydrogenase levels) and a few genetical and molecular markers (CAIX, B7-H1, and B7-H4). A few integrating systems have been proposed and validated, integrating both clinical and pathological (UCLA Integrating Staging Systems, Kattan nomogram, and Sorbellini nomogram) or only pathological variables (SSIGN score).
conclusionsSeveral large and methodologically consistent studies have been published. The chance to integrate the data derived from each prognostic factor into prognostic algorithms and scores has allowed improving significantly the stratification of the prognosis of patients with RCC. The currently available prognostic systems can be further improved through the inclusion of molecular and genetic variables. Integrating prognostic systems should be used to design randomized controlled trials (RCTs), which will evaluate the efficacy of the new-targeted therapies in either neoadjuvant, adjuvant, or salvage treatments of patients with RCC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.