ArticleAntimicrobial agents and chemotherapy2008
Increasing incidence of linezolid-intermediate or -resistant, vancomycin-resistant Enterococcus faecium strains parallels increasing linezolid consumption.
Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 90 citations in OpenAlex.
- Vancomycin-ResistantAntibiotics (Basel, Switzerland) · 2025Review
- Duration of hospitalization increases the risk for long-term carriage of linezolid-resistant enterococci in critically ill patients.Antimicrobial resistance and infection control · 2025Article
- Metabolic Rewiring ofMetabolites · 2024Review
- Recent advances in the synthesis of new benzothiazole based anti-tubercular compounds.RSC advances · 2023Review
- Treatment ofAntibiotics (Basel, Switzerland) · 2023Review
- The Impact of an Antibiotic Stewardship Program on the Consumption of Specific Antimicrobials and Their Cost Burden: A Hospital-wide Intervention.Risk management and healthcare policy · 2020Article
- Linezolid-resistantJournal of family medicine and primary care · 2019Article
- Pharmacodynamics Of Linezolid-Plus-Fosfomycin Against Vancomycin-Susceptible And -Resistant Enterococci In Vitro And In Vivo Of AInfection and drug resistance · 2019Article
- Current Perspectives on Treatment of Gram-Positive Infections in India: What Is the Way Forward?Interdisciplinary perspectives on infectious diseases · 2019Review
- Vancomycin-resistant enterococcus infection in the hematopoietic stem cell transplant recipient: an overview of epidemiology, management, and prevention.F1000Research · 2018Review
- Addressing the Challenges of Tuberculosis: A Brief Historical Account.Frontiers in pharmacology · 2017Review
- Global Emergence and Dissemination of Enterococci as Nosocomial Pathogens: Attack of the Clones?Frontiers in microbiology · 2016Review
- Emergence of linezolid- and vancomycin-resistant Enterococcus faecium in a department for hematologic stem cell transplantation.Antimicrobial resistance and infection control · 2016Article
- Total syntheses and initial evaluation of [Ψ[C(═S)NH]Tpg⁴]vancomycin, [Ψ[C(═NH)NH]Tpg⁴]vancomycin, [Ψ[CH₂NH]Tpg⁴]vancomycin, and their (4-chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide antibiotics.Journal of the American Chemical Society · 2015Article
- Vancomycin-resistant enterococcal infections: epidemiology, clinical manifestations, and optimal management.Infection and drug resistance · 2015Review
- The first linezolid-resistant Enterococcus faecium in India: High level resistance in a patient with no previous antibiotic exposure.Avicenna journal of medicine · 2014Article
- Disposition of linezolid or daptomycin in Enterococcal bloodstream infections according to vancomycin resistant Enterococcus colonization.Antimicrobial resistance and infection control · 2014Article
- Discontinuation of reflex testing of stool samples for vancomycin-resistant enterococci resulted in increased prevalence.Infection control and hospital epidemiology · 2013Article
- Virulence of vancomycin-resistant Enterococcus faecium according to linezolid resistance and clinical outbreak status.Antimicrobial agents and chemotherapy · 2013Article
- Use of daptomycin in the treatment of vancomycin-resistant enterococcal urinary tract infections: a short case series.BMC urology · 2013Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical enterococcal resistance to linezolid is defined by the presence of the G2576T mutation. We evaluated the incidence of genetically proven linezolid resistance among vancomycin-resistant Enterococcus faecium strains and linezolid consumption for a possible association. A relationship was found (r(2) = 0.73, P = 0.03) and predicts increasing resistance with current trends of linezolid use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.