SynthesisCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2008
Screening and case-finding instruments for depression: a meta-analysis.
Synthesis in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02935504 (PRogram In Support of Moms), which is not on this map. Cited by 162 papers, 17 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PRogram In Support of Moms (PRISM): A Pilot Group Randomized Controlled Trial
Who cites it
162 citing papers in PubMed, 17 syntheses or guidelines pooled it.
- The Performance of Wearable Device-Based Artificial Intelligence in Detecting Depression: Systematic Review and Meta-Analysis.JMIR mental health · 2026Pooled it
- Text-Based Depression Estimation Using Machine Learning With Standard Labels: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- Interventions to improve the detection of depression in primary healthcare: systematic review.Systematic reviews · 2023Pooled it
- Suicidal behaviors and ideation during emerging viral disease outbreaks before the COVID-19 pandemic: A systematic rapid review.Preventive medicine · 2020Pooled it
- Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in adults.The Cochrane database of systematic reviews · 2016Pooled it
- Reliability and validity of depression assessment among persons with HIV in sub-Saharan Africa: systematic review and meta-analysis.Journal of acquired immune deficiency syndromes (1999) · 2014Pooled it
- Pooled it
- Universal mental health screening in pediatric primary care: a systematic review.Journal of the American Academy of Child and Adolescent Psychiatry · 2013Pooled it
- Effects of screening for psychological distress on patient outcomes in cancer: a systematic review.Journal of psychosomatic research · 2013Pooled it
- Recommendations on screening for depression in adults.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Guideline
- Pooled it
- Comparing the accuracy of brief versus long depression screening instruments which have been validated in low and middle income countries: a systematic review.BMC psychiatry · 2012Pooled it
- Case identification of depression in patients with chronic physical health problems: a diagnostic accuracy meta-analysis of 113 studies.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Pooled it
- Depression screening and treatment among nonpregnant women of reproductive age in the United States, 1990-2010.Preventing chronic disease · 2011Pooled it
- Risk of bias from inclusion of patients who already have diagnosis of or are undergoing treatment for depression in diagnostic accuracy studies of screening tools for depression: systematic review.BMJ (Clinical research ed.) · 2011Pooled it
- International comparison of clinicians' ability to identify depression in primary care: meta-analysis and meta-regression of predictors.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Pooled it
- Pooled it
- Clinical effectiveness of care managers in collaborative primary health care for patients with depression: 12- and 24-month follow-up of a pragmatic cluster randomized controlled trial.BMC primary care · 2022Trial
- Trial
- Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial.Arthritis care & research · 2018Trial
102 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundScreening and case-finding has been proposed as a simple, quick and cheap method to improve the quality of care for depression. We sought to establish the effectiveness of screening in improving the recognition of depression, the management of depression and the outcomes of patients with depression.
methodsWe performed a Cochrane systematic review of randomized controlled trials conducted in nonmental health settings that included case-finding or screening instruments for depression. We conducted a meta-analysis and explored heterogeneity using meta-regression techniques.
resultsSixteen studies with 7576 patients met our inclusion criteria. We found that the use of screening or case-finding instruments were associated with a modest increase in the recognition of depression by clinicians (relative risk [RR] 1.27, 95% confidence interval [CI] 1.02 to 1.59). Questionnaires, when administered to all patients and the results given to clinicians irrespective of baseline score, had no impact on recognition (RR 1.03, 95% CI 0.85 to 1.24). Screening or case finding increased the use of any intervention by a relative risk of 1.30 (95% CI 0.97 to 1.76). There was no evidence of influence on the prescription of antidepressant medications (RR 1.20, 95% CI 0.87 to 1.66). Seven studies provided data on outcomes of depression, and no evidence of an effect was found (standardized mean difference -0.02, 95% CI -0.25 to 0.20).
interpretationIf used alone, case-finding or screening questionnaires for depression appear to have little or no impact on the detection and management of depression by clinicians. Recommendations to adopt screening strategies using standardized questionnaires without organizational enhancements are not justified.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.