ArticlePlant physiology2008
AtOSA1, a member of the Abc1-like family, as a new factor in cadmium and oxidative stress response.
Article in Plant physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 84 citations in OpenAlex.
- ABC1K2 is involved in stress response and secondary metabolism during seed development in Arabidopsis thaliana.Plant cell reports · 2025Article
- Physiological, anatomical, and molecular responses of glanded and glandless cotton to chromium exposure.Frontiers in plant science · 2025Article
- Genome-wide identification and analysis of expression patterns of theFrontiers in plant science · 2024Article
- Identification of QTN-by-environment interactions and their candidate genes for soybean seed oil-related traits using 3VmrMLM.Frontiers in plant science · 2022Article
- Genome-wide identification of wheat ABC1K gene family and functional dissection ofFrontiers in plant science · 2022Article
- ABC1K10a, an atypical kinase, functions in plant salt stress tolerance.BMC plant biology · 2020Article
- Reducing Cadmium Accumulation in Plants: Structure-Function Relations and Tissue-Specific Operation of Transporters in the Spotlight.Plants (Basel, Switzerland) · 2020Review
- Regulator Network Analysis of Rice and Maize Yield-Related Genes.Frontiers in cell and developmental biology · 2020Article
- PI signal transduction and ubiquitination respond to dehydration stress in the red seaweed Gloiopeltis furcata under successive tidal cycles.BMC plant biology · 2019Article
- Differentiated transcriptional signatures in the maize landraces of Chiapas, Mexico.BMC genomics · 2017Article
- Cadmium Disrupts the Balance between Hydrogen Peroxide and Superoxide Radical by Regulating Endogenous Hydrogen Sulfide in the Root Tip ofFrontiers in plant science · 2017Article
- Phosphorylation of plastoglobular proteins in Arabidopsis thaliana.Journal of experimental botany · 2016Article
- The Role of the Atypical Kinases ABC1K7 and ABC1K8 in Abscisic Acid Responses.Frontiers in plant science · 2016Article
- Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis.Molecular cell · 2015Article
- A chloroplast membrane protein LTO1/AtVKOR involving in redox regulation and ROS homeostasis.Plant cell reports · 2013Article
- A chloroplast ABC1-like kinase regulates vitamin E metabolism in Arabidopsis.Plant physiology · 2013Article
- Loss of plastoglobule kinases ABC1K1 and ABC1K3 causes conditional degreening, modified prenyl-lipids, and recruitment of the jasmonic acid pathway.The Plant cell · 2013Article
- A mechanism implicating plastoglobules in thylakoid disassembly during senescence and nitrogen starvation.Planta · 2013Review
- Phylogenetic, expression, and bioinformatic analysis of the ABC1 gene family in Populus trichocarpa.TheScientificWorldJournal · 2013Article
- When proteomics reveals unsuspected roles: the plastoglobule example.Frontiers in plant science · 2013Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The analysis of gene expression in Arabidopsis (Arabidopsis thaliana) using cDNA microarrays and reverse transcription-polymerase chain reaction showed that AtOSA1 (A. thaliana oxidative stress-related Abc1-like protein) transcript levels are influenced by Cd2+ treatment. The comparison of protein sequences revealed that AtOSA1 belongs to the family of Abc1 proteins. Up to now, Abc1-like proteins have been identified in prokaryotes and in the mitochondria of eukaryotes. AtOSA1 is the first member of this family to be localized in the chloroplasts. However, despite sharing homology to the mitochondrial ABC1 of Saccharomyces cerevisiae, AtOSA1 was not able to complement yeast strains deleted in the endogenous ABC1 gene, thereby suggesting different function between AtOSA1 and the yeast ABC1. The atosa1-1 and atosa1-2 T-DNA insertion mutants were more affected than wild-type plants by Cd2+ and revealed an increased sensitivity toward oxidative stress (hydrogen peroxide) and high light. The mutants exhibited higher superoxide dismutase activities and differences in the expression of genes involved in the antioxidant pathway. In addition to the conserved Abc1 region in the AtOSA1 protein sequence, putative kinase domains were found. Protein kinase assays in gelo using myelin basic protein as a kinase substrate revealed that chloroplast envelope membrane fractions from the AtOSA1 mutant lacked a 70-kD phosphorylated protein compared to the wild type. Our data suggest that the chloroplast AtOSA1 protein is a new factor playing a role in the balance of oxidative stress.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.