ArticleNeuro-oncology2008
Patients' perception of the informed consent process for neurooncology clinical trials.
Article in Neuro-oncology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Participants' understanding of informed consent in clinical trials: A systematic review and updated meta-analysis.PloS one · 2024Pooled it
- Participants' understanding of informed consent in clinical trials over three decades: systematic review and meta-analysis.Bulletin of the World Health Organization · 2015Pooled it
- Using digital multimedia to improve parents' and children's understanding of clinical trials.Archives of disease in childhood · 2015Trial
- Emerging trends in cell-based therapies: contemporary advances and ethical considerations in translational neurosurgical oncology.Journal of neuro-oncology · 2025Review
- Understanding and processing informed consent during data-intensive health research in sub-Saharan Africa: challenges and opportunities from a multilingual perspective.Research ethics · 2025Article
- Mapping patient encounters to identify recruitment timepoints after brain tumour surgery: a cohort and cross-sectional study.BMJ open quality · 2025Article
- Patient knowledge of surgical informed consent and shared decision-making process among surgical patients in Ethiopia: a systematic review and meta-analysis.Patient safety in surgery · 2024Article
- Patient, Relative and Staff Experiences of Clinical Trial Participation in Neurooncology: "Maybe You Can Also Show the Positive, No Matter How It Ends".Cancer management and research · 2024Article
- Current Applications of VR/AR (Virtual Reality/Augmented Reality) in Pediatric Neurosurgery.Advances and technical standards in neurosurgery · 2024Review
- Social Determinants of Health and Informed Consent Comprehension for Pediatric Cancer Clinical Trials.JAMA network open · 2023Article
- Guardians and research staff experiences and views about the consent process in hospital-based paediatric research studies in urban Malawi: A qualitative study.BMC medical ethics · 2022Article
- An evaluation of the process of informed consent: views from research participants and staff.Trials · 2021Article
- A Blockchain-Based Consent Platform for Active Assisted Living: Modeling Study and Conceptual Framework.Journal of medical Internet research · 2020Article
- Racial/Ethnic Differences in Comprehension of Biospecimen Collection: a Nationwide University of Rochester Cancer Center NCI Community Oncology Research Program Study.Journal of cancer education : the official journal of the American Association for Cancer Education · 2020Article
- Psychometric Development of the Research and Knowledge Scale.Medical care · 2017Article
- Neuro-oncology: Under-recognized mental incapacity in brain tumour patients.Nature reviews. Neurology · 2014Article
- Strengths and weaknesses of guideline approaches to safeguard voluntary informed consent of patients within a dependent relationship.BMC medicine · 2014Review
- The quality of informed consent: mapping the landscape. A review of empirical data from developing and developed countries.Journal of medical ethics · 2012Review
- Assessing research participants' perceptions of their clinical research experiences.Clinical and translational science · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The informed consent process is a cornerstone of modern medical research. This study was conducted to explore the process in the context of neurooncology clinical trials. Qualitative methodology and analysis were used on open-ended, face-to-face interviews conducted with 21 patients. Six comprehensive themes emerged: (1) general understanding of the objectives and purpose of clinical trials was good, (2) recall of risks was low, (3) patients did not believe that their care would be compromised by forgoing the clinical trial, (4) patients felt participation was voluntary and free of coercion, (5) patients would not have withdrawn from the trial in the event of complications, and (6) patients were satisfied with the informed consent process. Informed consent is a dynamic process; when appropriately executed, it can be a powerful safeguard protecting patient autonomy. If sufficient time is allowed to deliberate participation and ample opportunity is provided for information sharing and disclosure, researchers can be confident that participants are knowledgeable about the trial and aware of their rights.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.