Aging and defective healing, adverse remodeling, and blunted post-conditioning in the reperfused wounded heart.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Young Mice Exhibit Increased Relative Ventricular Remodeling After AMI-A Longitudinal CMR Study.Aging cell · 2026
   Article
2. Comparison of Myocardial Function in Young and Old Mice During Acute Myocardial Infarction: A Cardiac Magnetic Resonance Study.Diagnostics (Basel, Switzerland) · 2025
   Article
3. Clinical benefits of evolocumab in diabetic patients with STEMI undergoing PCI: a retrospective study.American journal of translational research · 2025
   Article
4. The Senescent Heart-"Age Doth Wither Its Infinite Variety".International journal of molecular sciences · 2024
   Review
5. Calcific Aortic Valve Disease: Part 2-Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility.Journal of cardiovascular translational research · 2016
   Review
6. The effects of aging on apoptosis following myocardial infarction.Cardiovascular therapeutics · 2013
   Article
7. Aging and Cardiac Fibrosis.Aging and disease · 2011
   Article
8. STEMI and heart failure in the elderly: role of adverse remodeling.Heart failure reviews · 2010
   Review
9. Role of osteopontin in heart failure associated with aging.Heart failure reviews · 2010
   Review
10. The role of inflammatory and fibrogenic pathways in heart failure associated with aging.Heart failure reviews · 2010
    Review
11. Role of healing-specific-matricellular proteins and matrix metalloproteinases in age-related enhanced early remodeling after reperfused STEMI in dogs.Molecular and cellular biochemistry · 2009
    Article

Corrections and comments

• Comment on
  Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction.2008
• Comment on
  Aging mouse hearts are refractory to infarct size reduction with post-conditioning.2008

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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