ArticlePathology oncology research : POR2008
SDF-1 and CCR5 genes polymorphism in patients with head and neck cancer.
Article in Pathology oncology research : POR, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- The SDF-1 rs1801157 Polymorphism is Associated with Cancer Risk: An Update Pooled Analysis and FPRP Test of 17,876 Participants.Scientific reports · 2016Pooled it
- CXCL12 G801A polymorphism and cancer risk: An updated meta-analysis.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2015Pooled it
- CCL5-403, CCR5-59029, and Delta32 polymorphisms and cancer risk: a meta-analysis based on 20,625 subjects.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Pooled it
- An Immune Feature-Based, Three-Gene Scoring System for Prognostic Prediction of Head-and-Neck Squamous Cell Carcinoma.Frontiers in oncology · 2021Article
- Association analysis and allelic distribution of deletion in CC chemokine receptor 5 gene (CCR5Δ32) among breast cancer patients of Pakistan.Molecular biology reports · 2019Article
- The frequency of CCR5 promoter polymorphisms and CCR5 Δ 32 mutation in Iranian populations.Iranian journal of basic medical sciences · 2015Review
- Article
- SDF-1alpha G801A polymorphism in Southern Iranian patients with colorectal and gastric cancers.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2013Article
- CXCL12 G801A polymorphism is associated with an increased risk of benign salivary gland tumors in the Chinese population.Medical oncology (Northwood, London, England) · 2012Article
- Genetic variants of SDF-1 and CXCR4 genes in endometrial carcinoma.Molecular biology reports · 2012Article
- Study the polymorphism of CYP3A5 and CYP3A4 loci in Iranian population with laryngeal squamous cell carcinoma.Molecular biology reports · 2011Article
- Analysis of chemokine and chemokine receptor expression in squamous cell carcinoma of the head and neck (SCCHN) cell lines.Radiation and environmental biophysics · 2011Article
- Article
- SDF1-3' G801A polymorphisms in Polish patients with systemic lupus erythematosus.Molecular biology reports · 2010Article
- SDF1-3' a gene polymorphism is associated with laryngeal cancer.Pathology oncology research : POR · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The frequency of SDF1-3'A and CCR5Delta32 in patients with head and neck cancer were determined in this study. The frequencies of alleles and genotypes of SDF-1 and CCR5 were assessed by PCR method in 156 patients with malignant head and neck cancer, 125 (80.1%) cases with squamous cell carcinoma and 31 (19.9%) cases with salivary gland tumors and compared with 262 age-sex matched healthy control individuals. SDF-1 genotypes in patients with SCC of head and neck, but not with salivary gland tumors, showed a statistically significant difference compared to the normal group (P < 0.005 for SCC and P = 0.3 for salivary gland tumors). There were no significant differences in the frequencies of SDF1-3'A allele, CCR5 genotypes and alleles between patients and controls. Based on the present study SDF1-3A may be associated with the susceptibility of patients to SCC of head and neck cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.