Evidence map›Paper›PMID 18386136›Full record

ReviewClinical & experimental metastasis2009

Influence of diet on metastasis and tumor dormancy.

Ann F Chambers

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & experimental metastasis, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Mouse Models of Metastasis and Dormancy.Cold Spring Harbor perspectives in medicine · 2024
    Review
  2. Article
  3. Review
  4. Review
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  7. Metastasis review: from bench to bedside.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Recent advances in colorectal cancer research: the microenvironment impact.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2011
    Article
  15. Controversies in clinical cancer dormancy.Proceedings of the National Academy of Sciences of the United States of America · 2011
    Review
  16. Review
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ann F ChambersDepartment of Oncology, University of Western Ontario, London, ON, Canada. ann.chambers@Lhsc.on.ca

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor metastasis is responsible for most cancer deaths, and can occur after long periods of tumor dormancy. Information learned from experimental studies on tumor metastasis and dormancy is shedding light on mechanisms responsible and possible therapeutic approaches. 'Seed' (the cancer cell) and 'soil' (the microenvironment of the secondary organ) factors contribute to metastatic outcome. This review considers the possibility that various dietary components may affect both 'seed' and 'soil' compartments, thereby influencing the growth of metastases, and discusses an experimental study on dietary genistein that illustrates this concept. While studies on human diet are complex, the possibility that relatively non-toxic dietary intervention strategies could impact on metastasis and patient survival is attractive and worthy of further study in appropriate experimental models of metastasis and tumor dormancy.

Indexed as

DietNeoplasm MetastasisAnimalsBody Mass IndexDietary SupplementsGenisteinMiceNeoplasms, ExperimentalRecurrenceGenistein

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.