ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2008
Physical sequelae and depressive symptoms in gynecologic cancer survivors: meaning in life as a mediator.
Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Religiosity/Spirituality and Physiological Markers of Health.Journal of religion and health · 2020Pooled it
- Pooled it
- Relations of meaning in life and sense of coherence to distress in cancer patients: a meta-analysis.Psycho-oncology · 2016Pooled it
- The Fatigue Symptom Inventory: a systematic review of its psychometric properties.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2010Pooled it
- Meaning-Centered Pain Coping Skills Training: A Pilot Feasibility Trial of a Psychosocial Pain Management Intervention for Patients with Advanced Cancer.Journal of palliative medicine · 2022Trial
- The course and predictors of perceived unsupportive responses by family and friends among women newly diagnosed with gynecological cancers.Translational behavioral medicine · 2019Trial
- Mediators of a culturally-sensitive intervention for suicidal African American women.Journal of clinical psychology in medical settings · 2013Trial
- Resilience, Positive Coping, and Quality of Life Among Women Newly Diagnosed With Gynecological Cancers.Cancer nursingTrial
- The relationship between cancer patients' spiritual needs, quality of life and depression levels: A correlational study.Palliative & supportive care · 2025Article
- Enhancing meaning in the face of advanced cancer and pain: Qualitative evaluation of a meaning-centered psychosocial pain management intervention.Palliative & supportive care · 2020Article
- Psychobiological factors of resilience and depression in late life.Translational psychiatry · 2019Review
- Taking on the stress-depression link: Meaning as a resource in adolescence.Journal of adolescence · 2018Article
- Development and Validation of a Multidisciplinary Mobile Care System for Patients With Advanced Gastrointestinal Cancer: Interventional Observation Study.JMIR mHealth and uHealth · 2018Article
- Purpose in life predicts allostatic load ten years later.Journal of psychosomatic research · 2015Article
- Integrating positive psychology into health-related quality of life research.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015Review
- Emotional and sexual concerns in women undergoing pelvic surgery and associated treatment for gynecologic cancer.Translational andrology and urology · 2015Review
- Positive changes after breast cancer: A qualitative study.Journal of education and health promotion · 2015Article
- Care-seeking behavior of Japanese gynecological cancer survivors suffering from adverse effects.BMC women's health · 2013Article
- The role of spiritual experiences and activities in the relationship between chronic illness and psychological well-being.Journal of religion and health · 2012Article
- Gynecologic care for breast cancer survivors: assisting in the transition to wellness.American journal of obstetrics and gynecology · 2012Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundContinuing symptoms and poor health following cancer treatments may alter meaning in life for cancer survivors. Gynecologic cancer survivors are particularly troubled with physical sequelae. In addition, for the most common sites of disease, such as breast and gynecologic cancers, the prevalence of depression is also high. PURPOSE: This study tests meaning in life as a mechanism for the relationship between physical symptoms and depressive symptoms.
methodsGynecologic cancer survivors (N = 260) participated. Measures of physical sequelae (nurse rated symptoms/signs, patient-reported gynecologic symptoms), meaning in life (harmony, life purpose, spirituality, and conversely, confusion and loss), and depressive symptoms were obtained at the time of a routine clinical follow-up visit 2-10 years following the completion of treatment. Latent variables were defined, and structural equation modeling tested a mediator model.
resultsAnalyses support partial mediation. That is, survivors with more physical sequelae also reported lower levels of meaning in life, which was associated with higher levels of depressive symptoms.
conclusionsGynecologic cancer patients have been neglected in psychosocial research, and findings highlight the importance of existential issues in their lives. While many adjust well, those with persistent physical functioning deficits may experience depressive symptoms. By appreciating the role of meaning in their experience, we may help survivors foster their own growth and perspectives important for their future.
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