Evidence map›Paper›PMID 18386101›Full record

ArticleJournal of general internal medicine2008

Effects of disclosing financial interests on attitudes toward clinical research.

Kevin P Weinfurt, Mark A Hall, Michaela A Dinan, Venita DePuy, Joëlle Y Friedman, Jennifer S Allsbrook, Jeremy Sugarman

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Patient views on financial relationships between surgeons and surgical device manufacturers.Canadian journal of surgery. Journal canadien de chirurgie · 2015
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Scientific research and the public trust.Science and engineering ethics · 2011
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Kevin P WeinfurtCenter for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA. kevin.weinfurt@duke.edu
Mark A Hall
Michaela A Dinan
Venita DePuy
Joëlle Y Friedman
Jennifer S Allsbrook
Jeremy Sugarman
Clinical Research Institute · USDuke University · USJohns Hopkins University · USWake Forest University · US

Funding

Disclosing Conflict of Interest to Research ParticipantsR01HL075538 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SUGARMAN, JEREMY · 2004 to 2008
$2.9M
NHLBI NIH HHS R01 HL075538NHLBI NIH HHS R01HL075538-01
6 · The paper itself

Abstract

backgroundThe effects of disclosing financial interests to potential research participants are not well understood.

objectiveTo examine the effects of financial interest disclosures on potential research participants' attitudes toward clinical research. DESIGN AND

participantsComputerized experiment conducted with 3,623 adults in the United States with either diabetes mellitus or asthma, grouped by lesser and greater severity. Respondents read a description of a hypothetical clinical trial relevant to their diagnosis that included a financial disclosure statement. Respondents received 1 of 5 disclosure statements. MEASUREMENTS: Willingness to participate in the hypothetical clinical trial, relative importance of information about the financial interest, change in trust after reading the disclosure statement, surprise regarding the financial interest, and perceived effect of the financial interest on the quality of the clinical trial.

resultsWillingness to participate in the hypothetical clinical trial did not differ substantially among the types of financial disclosures. Respondents viewed the disclosed information as less important than other factors in deciding to participate. Disclosures were associated with some respondents trusting the researchers less, although trust among some respondents increased. Most respondents were not surprised to learn of financial interests. Researchers owning equity were viewed as more troubling than researchers who were compensated for the costs of research through per capita payments.

conclusionsAside from a researcher holding an equity interest, the disclosure to potential research participants of financial interests in research, as recommended in recent policies, is unlikely to affect willingness to participate in research.

Indexed as

Decision MakingDisclosurePatient ParticipationAdultAgedAsthmaBiomedical ResearchClinical Trials as TopicConflict of InterestData CollectionDiabetes MellitusFemaleHumansMaleMiddle AgedResearch Subjects

Identifiers

PMID18386101
PMCPMC2517900
OpenAlexW2060005584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.