ArticleKorean journal of radiology
Advanced gastric cancer and perfusion imaging using a multidetector row computed tomography: correlation with prognostic determinants.
Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Gastric cancer staging with dual energy spectral CT imaging.PloS one · 2013Trial
- Predicting human epidermal growth factor receptor 2 status of patients with gastric cancer by computed tomography and clinical features.Gastroenterology report · 2024Article
- pT1-2 gastric cancer with lymph node metastasis predicted by tumor morphologic features on contrast-enhanced computed tomographyDiagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- Imaging in Gastric Cancer: Current Practice and Future Perspectives.Diagnostics (Basel, Switzerland) · 2023Review
- Quantitative parameters in novel spectral computed tomography: Assessment of Ki-67 expression in patients with gastric adenocarcinoma.World journal of gastroenterology · 2023Article
- Value of multiphase contrast-enhanced CT with three-dimensional reconstruction in detecting depth of infiltration, lymph node metastasis, and extramural vascular invasion of gastric cancer.Journal of gastrointestinal oncology · 2021Article
- Dynamic Contrast-Enhanced Ultrasound of Gastric Cancer: Correlation with Perfusion CT and Histopathology.Korean journal of radiology · 2019Article
- Prediction of Treatment Outcome of Chemotherapy Using Perfusion Computed Tomography in Patients with Unresectable Advanced Gastric Cancer.Korean journal of radiology · 2019Article
- Imaging biomarkers in upper gastrointestinal cancers.BJR open · 2019Review
- CT Perfusion evaluation of gastric cancer: correlation with histologic type.European radiology · 2018Article
- Association between spectral computed tomography images and clinicopathological features in advanced gastric adenocarcinoma.Oncology letters · 2017Article
- Spectral computed tomography in advanced gastric cancer: Can iodine concentration non-invasively assess angiogenesis?World journal of gastroenterology · 2017Article
- Diagnostic value of CT perfusion imaging for parotid neoplasms.Dento maxillo facial radiology · 2014Article
- Grading of uterine cervical cancer by using the ADC difference value and its correlation with microvascular density and vascular endothelial growth factor.European radiology · 2013Article
- The value of perfusion CT in predicting the short-term response to synchronous radiochemotherapy for cervical squamous cancer.European radiology · 2012Article
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8 authors.
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Abstract
objectiveTo investigate the relationship between the perfusion CT features and the clinicopathologically determined prognostic factors in advanced gastric cancer cases. MATERIALS AND
methodsA perfusion CT was performed on 31 patients with gastric cancer one week before surgery using a 16-channel multi-detector CT (MDCT) instrument. The data were analyzed with commercially available software to calculate tumor blood flow (BF), blood volume (BV), mean transit time (MTT), and permeability surface (PS). The microvessel density (MVD), was evaluated by immunohistochemical staining of the surgical specimens with anti-CD34. All of the findings were analyzed prospectively and correlated with the clinicopathological findings, which included histological grading, presence of lymph node metastasis, serosal involvement, distant metastasis, tumor, node, metastasis (TNM) staging, and MVD. The statistical analyses used included the Student's t-test and the Spearman rank correlation were performed in SPSS 11.5.
resultsThe mean perfusion values and MVD for tumors were as follows: BF (48.14+/-16.46 ml/100 g/min), BV (6.70+/-2.95 ml/100 g), MTT (11.75+/-4.02 s), PS (14.17+/-5.23 ml/100 g/min) and MVD (41.7+/-11.53). Moreover, a significant difference in the PS values was found between patients with or without lymphatic involvement (p = 0.038), as well as with different histological grades (p = 0.04) and TNM stagings (p = 0.026). However, BF, BV, MTT, and MVD of gastric cancer revealed no significant relationship with the clinicopathological findings described above (p > 0.05).
conclusionThe perfusion CT values of the permeable surface could serve as a useful prognostic indicator in patients with advanced gastric cancer.
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