ArticleJournal of pediatric psychology2009
Brief assessment of parents' attitudes toward testing minor children for hereditary breast/ovarian cancer genes: development and validation of the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS).
Article in Journal of pediatric psychology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 37 citations in OpenAlex.
- Maternal Communication of BRCA Risk to Adolescent and Young Adult Children: Implications for Supportive Care Intervention.Psycho-oncology · 2026Article
- Pediatric Oncology Patients With Germline Pathogenic Variants in Adult-Onset Cancer Predisposition Genes.JCO precision oncology · 2025Article
- Parental perspectives on the use of tumor molecular profiling and germline genetic testing during their children's cancer treatment.Familial cancer · 2025Article
- Effects of personal cancer history and genomic risk information on mothers' psychological adaptation to inherited breast/ovarian cancer syndrome.Psychology, health & medicine · 2025Article
- Parent and patient knowledge and attitudes about cancer predisposition syndrome genetic testing in pediatric oncology: Understanding sociodemographic and parent-child differences.Cancer reports (Hoboken, N.J.) · 2024Article
- Measuring high-risk parents' opinions about direct-to-consumer genetic testing for adult-onset inherited cancer syndromes in their adolescent and young adult children.Journal of genetic counseling · 2023Article
- Improving our model of cascade testing for hereditary cancer risk by leveraging patient peer support: a concept report.Hereditary cancer in clinical practice · 2021Article
- Cancer genetic health communication in families tested for hereditary breast/ovarian cancer risk: a qualitative investigation of impact on children's genetic health literacy and psychosocial adjustment.Translational behavioral medicine · 2019Article
- Maternal perceptions of BRCA genetic counseling communication processes about disclosing cancer risk information to children and adult relatives.Psycho-oncology · 2018Article
- Modeling the dyadic effects of parenting, stress, and coping on parent-child communication in families tested for hereditary breast-ovarian cancer risk.Familial cancer · 2016Article
- How Much Control Do Children and Adolescents Have over Genomic Testing, Parental Access to Their Results, and Parental Communication of Those Results to Others?The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2015Article
- Distress and the parenting dynamic among BRCA1/2 tested mothers and their partners.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2014Article
- Effects of undergoing multiplex genetic susceptibility testing on parent attitudes towards testing their children.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2014Article
- Psychometric properties of the Pediatric Testing Attitudes Scale-Diabetes (P-TAS-D) for parents of children undergoing predictive risk screening.Pediatric diabetes · 2013Article
- Decisional outcomes of maternal disclosure of BRCA1/2 genetic test results to children.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2013Article
- Unintended diagnosis of Von Hippel Lindau syndrome using Array Comparative Genomic Hybridization (CGH): counseling challenges arising from unexpected information.Journal of genetic counseling · 2013Article
- Growing up in the genomic era: implications of whole-genome sequencing for children, families, and pediatric practice.Annual review of genomics and human genetics · 2013Review
- Parenting through genetic uncertainty: themes in the disclosure of breast cancer risk information to children.Genetic testing and molecular biomarkers · 2012Article
- Article
- Primary care providers' willingness to recommend BRCA1/2 testing to adolescents.Familial cancer · 2010Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
objectivePredictive genetic testing for hereditary breast/ovarian cancer risk (BRCA1/2 testing) is not recommended for minor children due to its lack of immediate medical benefit and potential psychological risk. Yet, tested mothers are often interested in learning about their children's cancer risks via pediatric BRCA1/2 testing, raising a host of bioethical concerns. However, no reliable or valid tool exists to formally gauge parents' interest in such testing. The aim of this study was to develop and evaluate a new measure for use in genetic research and consultation, known as the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS).
methodsAfter pretest genetic counseling and provision of a blood sample for BRCA1/2 testing, the P-TAS was administered to 187 mothers of children between 8- and 21-years-old. The measure was also given to 96 of the mothers' nontested co-parents. Analyses of the factor structure and psychometric properties of the measure were performed in mothers and confirmed in their co-parents.
resultsThe two factors of the P-TAS, labeled Attitudes and Beliefs (Factor 1) and Decision Making and Communication (Factor 2), accounted for 62.9% of the variance and were reliable (Cronbach's coefficient alphas =.70 and .90, respectively); the structure and properties were largely confirmed among co-parents. Validity was indicated through its convergence with related constructs.
conclusionsThis new tool may be integrated into genetic counseling research to better assess parents' attitudes and interests in pediatric BRCA1/2 testing. Such information may help guide ongoing discussions about the appropriateness of testing in adolescent or young adult children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.