ReviewDevelopmental neurobiology2008
Imaging second messenger dynamics in developing neural circuits.
Review in Developmental neurobiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- A molecular integrator of sleep duration and interruption.bioRxiv : the preprint server for biology · 2026Article
- Fluorescent sensors for intracellular signaling in the brain: imaging neurons, glia, and vascular cells.Neurophotonics · 2025Article
- Prostaglandin E2 depolarises sensory axons in vitro in an ANO1 and Nav1.8 dependent manner.Scientific reports · 2024Article
- Sensitive genetically encoded sensors for population and subcellular imaging of cAMP in vivo.Nature methods · 2022Article
- Phosphorylation of cysteine string protein-α up-regulates the frequency of cholinergic wavesVisual neuroscience · 2022Article
- Genetically encoded sensors towards imaging cAMP and PKA activity in vivo.Journal of neuroscience methods · 2021Review
- Presynaptic SNAP-25 regulates retinal waves and retinogeniculate projection via phosphorylation.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Article
- Signaling: Spatial regulation of axonal cAMP.Nature chemical biology · 2017Article
- GABAA receptor-mediated tonic depolarization in developing neural circuits.Molecular neurobiology · 2014Review
- cAMP signaling microdomains and their observation by optical methods.Frontiers in cellular neuroscience · 2014Review
- Article
- Adenosine A(2A) receptor up-regulates retinal wave frequency via starburst amacrine cells in the developing rat retina.PloS one · 2014Article
- Striatal neurones have a specific ability to respond to phasic dopamine release.The Journal of physiology · 2013Article
- Imaging adhesion and signaling dynamics in Xenopus laevis growth cones.Developmental neurobiology · 2012Review
- Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa.The Journal of biological chemistry · 2011Article
- Imaging cytoplasmic cAMP in mouse brainstem neurons.BMC neuroscience · 2009Article
- Imaging the glycome.Proceedings of the National Academy of Sciences of the United States of America · 2009Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
A characteristic feature of developing neural circuits is that they are spontaneously active. There are several examples, including the retina, spinal cord, and hippocampus, where spontaneous activity is highly correlated among neighboring cells, with large depolarizing events occurring with a periodicity on the order of minutes. One likely mechanism by which neurons can "decode" these slow oscillations is through activation of second messenger cascades that either influence transcriptional activity or drive posttranslational modifications. Here, we describe recent experiments where imaging has been used to characterize slow oscillations in the cAMP/PKA second messenger cascade in retinal neurons. We review the latest techniques in imaging this specific second messenger cascade, its intimate relationship with changes in intracellular calcium concentration, and several hypotheses regarding its role in neurodevelopment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.