Evidence map›Paper›PMID 18382739›Full record

ReviewThe Journal of clinical investigation2008

Malaria: progress, perils, and prospects for eradication.

Brian M Greenwood, David A Fidock, Dennis E Kyle, Stefan H I Kappe, Pedro L Alonso, Frank H Collins, Patrick E Duffy

Abstract readReview
In one paragraph

Review in The Journal of clinical investigation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 246 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
246citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

246 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. ACS omega · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Microorganisms · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Mechanism of Immune Evasion in Mosquito-Borne Diseases.Pathogens (Basel, Switzerland) · 2023
    Review
  20. Genetic Diversity ofTropical medicine and infectious disease · 2023
    Article

186 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brian M GreenwoodDepartment of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
David A Fidock
Dennis E Kyle
Stefan H I Kappe
Pedro L Alonso
Frank H Collins
Patrick E Duffy

Funding

Artemisinin-induced Dormancy &Malaria Treatment FailureR01AI058973 · NIAID · U.S. WALTER REED ARMY INST OF RESEARCH · PI KYLE, DENNIS E · 2005 to 2008
$1.1M
NIAID NIH HHS R01 AI058973
6 · The paper itself

Abstract

There are still approximately 500 million cases of malaria and 1 million deaths from malaria each year. Yet recently, malaria incidence has been dramatically reduced in some parts of Africa by increasing deployment of anti-mosquito measures and new artemisinin-containing treatments, prompting renewed calls for global eradication. However, treatment and mosquito control currently depend on too few compounds and thus are vulnerable to the emergence of compound-resistant parasites and mosquitoes. As discussed in this Review, new drugs, vaccines, and insecticides, as well as improved surveillance methods, are research priorities. Insights into parasite biology, human immunity, and vector behavior will guide efforts to translate parasite and mosquito genome sequences into novel interventions.

Indexed as

AnimalsAntimalarialsDrug ResistanceHumansMalariaMalaria VaccinesPlasmodium falciparumAntimalarialsMalaria Vaccines

Identifiers

PMID18382739
PMCPMC2276780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.