Evidence map›Paper›PMID 18382613›Full record

ArticleMediators of inflammation2008

Effects of radix adenophorae and cyclosporine A on an OVA-induced murine model of asthma by suppressing to T cells activity, eosinophilia, and bronchial hyperresponsiveness.

Seong-Soo Roh, Seung-Hyung Kim, Young-Cheol Lee, Young-Bae Seo

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Antioxidants (Basel, Switzerland) · 2022
    Article
  6. Turkish journal of chemistry · 2022
    Article
  7. Article
  8. Article
  9. Investigation of anti-asthmatic potential of dried fruits of Vitis vinifera L. in animal model of bronchial asthma.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Seong-Soo RohLaboratory of Herbology, College of Oriental Medicine, Daegu Hanny University, Daegu 706060, South Korea.
Seung-Hyung Kim
Young-Cheol Lee
Young-Bae Seo
Daejeon University · KRDaegu Haany University · KRSangji University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study is performed to investigate the inhibitory effects of Radix Adenophorae extract (RAE) on ovalbumin-induced asthma murine model. To study the anti-inflammatory and antiasthmatic effects of RAE, we examined the development of pulmonary eosinophilic inflammation and inhibitory effects of T cells in murine by RAE and cyclosporine A (CsA). We examined determination of airway hyperresponsiveness, flow cytometric analysis (FACS), enzyme-linked immunosorbent assay (ELISA), quantitative real time (PCR), hematoxylin-eosin staining, and Masson trichrome staining in lung tissue, lung weight, total cells, and eosinophil numbers in lung tissue. We demonstrated how RAE suppressed development on inflammation and decreased airway damage.

Indexed as

AnimalsAsthmaBronchial HyperreactivityBronchoalveolar Lavage FluidCD4-Positive T-LymphocytesCyclosporineCytokinesFemaleHumansImmunoglobulin EImmunosuppressive AgentsLungMiceMice, Inbred C57BLOvalbuminPlant ExtractsCyclosporineCytokinesImmunoglobulin EImmunosuppressive AgentsOvalbuminPlant Extracts

Identifiers

PMID18382613
PMCPMC2276601
OpenAlexW2049067793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.