Evidence map›Paper›PMID 18381085›Full record

ReviewBiochimica et biophysica acta2008

MicroRNA-206: the skeletal muscle-specific myomiR.

John J McCarthy

Open access · greenAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 238 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
238citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

238 citing papers in PubMed, 1 synthesis or guideline pooled it, 417 citations in OpenAlex.

  1. The Role of MicroRNAs in Patients with Amyotrophic Lateral Sclerosis.Journal of molecular neuroscience : MN · 2018
    Pooled it
  2. Trial
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  11. Optimal murine CD4Nature communications · 2026
    Article
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  17. Local Non-Coding Regulatory Elements in Muscular Dystrophies.International journal of molecular sciences · 2025
    Review
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  19. Review
  20. Review

178 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

John J McCarthyDepartment of Physiology, University of Kentucky Medical Center, 800 Rose St., Lexington, KY 40536-0298, USA. jjmcca2@uky.edu
University of Kentucky · US

Funding

SKELETAL MUSCLE HYPERTROPHY AND INTRACELLULAR SIGNALINGR01AR045617 · NIAMS · UNIVERSITY OF KENTUCKY · PI ESSER, KARYN A · 1999 to 2011
$2.9M
Circadian Regulation of Myod1 TranscriptionR03AR053641 · NIAMS · UNIVERSITY OF KENTUCKY · PI MCCARTHY, JOHN JOSEPH · 2007 to 2009
$217k
NIAMS NIH HHS AR053641NIAMS NIH HHS AR45617NIAMS NIH HHS R01 AR045617NIAMS NIH HHS R03 AR053641
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are a class of non-coding RNAs involved in post-transcriptional gene silencing. A small number of striated muscle-specific miRNAs have been identified and shown to have an important role in myogenesis, embryonic muscle growth and cardiac function and hypertrophy. One of these myomiRs (myo=muscle+miR=miRNA), miR-206, is unique in that it is only expressed in skeletal muscle. The purpose of this review is to discuss what is currently known about miR-206 and its function in myogenesis as well as propose potential new roles for miR-206 in skeletal muscle biology. The review is also intended to serve as a comprehensive resource for miR-206 with the hope of encouraging further research on the role of miR-206 in skeletal muscle.

Indexed as

AnimalsBase SequenceHumansMicroRNAsMolecular Sequence DataMuscle DevelopmentMuscle, SkeletalOrgan SpecificityMicroRNAs

Identifiers

PMID18381085
PMCPMC2656394
OpenAlexW2070294322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.