Evidence map›Paper›PMID 18378836›Full record

ArticlePsychiatric services (Washington, D.C.)2008

The impact of cost sharing on antidepressant use among older adults in British Columbia.

Philip S Wang, Amanda R Patrick, Colin R Dormuth, Jerry Avorn, Malcolm Maclure, Claire F Canning, Sebastian Schneeweiss

Abstract read
In one paragraph

Article in Psychiatric services (Washington, D.C.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Costs and benefits of free medications after myocardial infarction.Healthcare policy = Politiques de sante · 2009
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Philip S WangNational Institute of Mental Health, Bethesda, MD 20892-9629, USA. wangphi@mail.nih.gov
Amanda R Patrick
Colin R Dormuth
Jerry Avorn
Malcolm Maclure
Claire F Canning
Sebastian Schneeweiss

Funding

Effects of income-based drug charges on older PatientsR01AG021950 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SCHNEEWEISS, SEBASTIAN G. · 2003 to 2006
$1.3M
Remibursement Limits, Antidepressants, and OutcomesR01MH069772 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI WANG, PHILIP S · 2004 to 2005
$674k
Remibursement Limits, Antidepressants, and OutcomesU01MH069772 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI SCHNEEWEISS, SEBASTIAN G. · 2006 to 2007
$600k
CONSEQUENCES OF DRUG COST SHARING IN THE ELDERLYR01HS010881 · AHRQ · BRIGHAM AND WOMEN'S HOSPITAL · PI SCHNEEWEISS, SEBASTIAN G. · 2000 to 2006
$263k
AHRQ HHS 5-R01-HS-010881-07AHRQ HHS R01 HS010881NIA NIH HHS R01 AG021950NIA NIH HHS R01-AG-021950NIMH NIH HHS R01 MH069772NIMH NIH HHS R01-MH-069772NIMH NIH HHS U01 MH069772
6 · The paper itself

Abstract

objectiveAntidepressant therapies are underused among older adults and could be further curtailed by patient cost-sharing requirements. The authors studied the effects of two sequential cost-sharing policies in a large, stable population of all British Columbia seniors: change from full prescription coverage to 10-25 dollars copayments (copay) in January 2002 and replacement with income-based deductibles and 25% coinsurance in May 2003.

methodsPharmaNet data were used to calculate monthly dispensing of antidepressants (in imipramine-equivalent milligrams) among all British Columbia residents age 65 and older beginning January 1997 through December 2005. Monthly rates of starting and stopping antidepressants were calculated. Population-level patterns over time were plotted, and the effects of implementing cost-sharing policies on antidepressant use, initiation, and stopping were examined in segmented linear regression models.

resultsImplementation of the copay policy was not associated with significant changes in level of antidepressant dispensing or the rate of dispensing growth. Subsequent implementation of the income-based deductible policy also did not lead to a significant change in dispensing level but led to a significant (p=.02) decrease in the rate of growth of antidepressant dispensing. The copay policy was associated with a significant (p=.01) drop in the frequency of antidepressant initiation among persons with depression. Income-based deductibles reduced the rate of increase in antidepressant initiation over time. Implementation of the copay and income-based deductible policies did not have significant effects on stopping rates.

conclusionsIntroducing new forms of medication cost sharing appears to have the potential to reduce some use and initiation of antidepressant therapy by seniors. The clinical consequences of such reduced use need to be clarified.

Indexed as

Adrenergic Uptake InhibitorsAgedAntidepressive AgentsBritish ColumbiaCost SharingDepressive DisorderDrug TherapyFemaleHealth PolicyHumansImipramineMaleMiddle AgedPrevalenceAdrenergic Uptake InhibitorsAntidepressive AgentsImipramine

Identifiers

PMID18378836
PMCPMC2884181

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.