Evidence map›Paper›PMID 18378707›Full record

ArticleAntimicrobial agents and chemotherapy2008

Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia.

Ralf R Reinert, Olga Y Filimonova, Adnan Al-Lahham, Svetlana A Grudinina, Elena N Ilina, Linda M Weigel, Sergey V Sidorenko

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ralf R ReinertInstitute for Medical Microbiology, National Reference Center for Streptococci, University Hospital (RWTH), Aachen, Germany.
Olga Y Filimonova
Adnan Al-Lahham
Svetlana A Grudinina
Elena N Ilina
Linda M Weigel
Sergey V Sidorenko

Funding

PHS HHS 2460/61
6 · The paper itself

Abstract

Among 76 macrolide-nonsusceptible Streptococcus pneumoniae isolates collected between 2003 and 2005 from Central Russia, the resistance mechanisms detected in the isolates included erm(B) alone (50%), mef alone [mef(E), mef(I), or a different mef subclass; 19.7%], or both erm(B) and mef(E) (30.3%). Isolates with dual resistance genes [erm(B) and mef(E)] belonged to clonal complex CC81 or CC271.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsClindamycinDrug Resistance, BacterialErythromycinHumansMacrolidesMembrane ProteinsMethyltransferasesMicrobial Sensitivity TestsMolecular Sequence DataPhenotypePneumococcal InfectionsRussiaSequence Analysis, DNAStreptococcus pneumoniaeAnti-Bacterial AgentsBacterial ProteinsClindamycinErythromycinMacrolidesMefA protein, StreptococcusMefE protein, Streptococcus pneumoniaeMembrane ProteinsMethyltransferases

Identifiers

PMID18378707
PMCPMC2415785

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.