Evidence map›Paper›PMID 18377795›Full record

ReviewCurrent gastroenterology reports2007

Small bowel bacterial overgrowth: a negative factor in gut adaptation in pediatric SBS.

Conrad R Cole, Thomas R Ziegler

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Post-endoscopic fever and infection in paediatric patients with intestinal failure.Journal of pediatric gastroenterology and nutrition · 2025
    Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. The Pathogenesis of Resection-Associated Intestinal Adaptation.Cellular and molecular gastroenterology and hepatology · 2016
    Review
  11. Article
  12. Small bowel resection induces long-term changes in the enteric microbiota of mice.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015
    Article
  13. Review
  14. Article
  15. Article
  16. Intestinal mucosal atrophy and adaptation.World journal of gastroenterology · 2012
    Review
  17. Review
  18. Small intestinal bacterial overgrowth syndrome.World journal of gastroenterology · 2010
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Conrad R ColeDivision of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 2015 Uppergate Drive, Atlanta, GA 30322, USA. Conrad_cole@oz.ped.emory.edu
Thomas R Ziegler

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Mentored Clinical Research Scholar ProgramK12RR017643 · NCRR · EMORY UNIVERSITY · PI BLUMBERG, HENRY M · 2002 to 2006
$5.1M
NCATS NIH HHS UL1 TR000454NCRR NIH HHS K12RR17643
6 · The paper itself

Abstract

Small bowel bacterial overgrowth (SBBO) is common in infants and children with short bowel syndrome (SBS). Its occurrence is due to alterations in anatomy, motility, and secretion, which promote the abnormal growth of bacteria. SBBO is associated with significant clinical problems, including prolonged dependence on parenteral nutrition, liver injury, and malabsorption. A major clinical challenge is in making the correct diagnosis of bacterial overgrowth. Management of this disorder is still poorly understood and should be evaluated adequately. This review addresses the current understanding of bacteria in the intestines and issues related to bacterial overgrowth in pediatric SBS.

Indexed as

Adaptation, PhysiologicalAnti-Bacterial AgentsBlind Loop SyndromeBreath TestsChildColony Count, MicrobialComorbidityDigestive System Surgical ProceduresEnteral NutritionHumansIntestinal AbsorptionIntestinal MucosaIntestine, SmallLiver DiseasesProbioticsRisk FactorsAnti-Bacterial Agents

Identifiers

PMID18377795
OpenAlexW2002418675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.