ArticleCurrent atherosclerosis reports2007
Monounsaturated fatty acids and atherosclerosis: opposing views from epidemiology and experimental animal models.
Article in Current atherosclerosis reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Mediterranean and MIND Diets Containing Olive Biophenols Reduces the Prevalence of Alzheimer's Disease.International journal of molecular sciences · 2019Review
- Epigenetic control of lipid metabolism: implications for lifespan and healthspan.Cardiovascular research · 2018Article
- The monounsaturated fatty acid oleate is the major physiological toxic free fatty acid for human beta cells.Nutrition & diabetes · 2017Article
- Anti-obesity effect of a traditional Chinese dietary habit-blending lard with vegetable oil while cooking.Scientific reports · 2017Article
- Seeking a unique lipid signature predicting cardiovascular disease risk.Circulation · 2014Article
- Nutrition, nonalcoholic fatty liver disease and the microbiome: recent progress in the field.Current opinion in lipidology · 2014Review
- Article
- The role of nutraceutical supplements in the treatment of dyslipidemia.Journal of clinical hypertension (Greenwich, Conn.) · 2012Article
- Pretreatment with n-6 PUFA protects against subsequent high fat diet induced atherosclerosis--potential role of oxidative stress-induced antioxidant defense.Atherosclerosis · 2012Article
- The role of reducing intakes of saturated fat in the prevention of cardiovascular disease: where does the evidence stand in 2010?The American journal of clinical nutrition · 2011Review
- Dietary monounsaturated fatty acids appear not to provide cardioprotection.Current atherosclerosis reports · 2010Review
- Dietary n-3 LCPUFA from fish oil but not alpha-linolenic acid-derived LCPUFA confers atheroprotection in mice.Journal of lipid research · 2010Article
- Nutrigenomics in cardiovascular medicine.Circulation. Cardiovascular genetics · 2009Review
- LDL cholesteryl oleate as a predictor for atherosclerosis: evidence from human and animal studies on dietary fat.Journal of lipid research · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A substantial body of epidemiologic data has shed light on the potential protective effects of the Mediterranean diet against atherosclerosis in humans. Many believe the reason the Mediterranean diet is atheroprotective is the elevated consumption of olive oil, an oil poor in saturated fatty acids (SFA) and highly enriched in monounsaturated fatty acids (MUFA). Based on human feeding studies, the American Heart Association and the US Food and Drug Administration have advocated for the consumption of MUFA as a more healthy replacement for SFA. However, using experimental animal models in which extent of atherosclerosis can be directly measured following dietary intervention, it has been demonstrated that MUFA-enriched diets are not atheroprotective when compared with SFA-enriched diets. Hence, the current body of experimental evidence refutes the idea that MUFAs per se are atheroprotective; therefore much additional work is needed to determine which aspects of the Mediterranean diet are indeed heart healthy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.