Evidence map›Paper›PMID 18377778›Full record

ReviewCurrent allergy and asthma reports2008

Importance of mold allergy in asthma.

Jay M Portnoy, Charles S Barnes, Kevin Kennedy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Medicina (Kaunas, Lithuania) · 2025
    Review
  3. Allergy to Fungi in Veterinary Medicine:Journal of fungi (Basel, Switzerland) · 2022
    Review
  4. Article
  5. Fungi and Atopy.Clinical reviews in allergy & immunology · 2019
    Review
  6. Association of molds and metrological parameters to frequency of severe asthma exacerbation.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019
    Article
  7. The infant gut bacterial microbiota and risk of pediatric asthma and allergic diseases.Translational research : the journal of laboratory and clinical medicine · 2017
    Review
  8. Article
  9. Article
  10. Asthma associations in children attending a museum of science.International journal of environmental research and public health · 2013
    Article
  11. Article
  12. Article
  13. New-onset adult asthma in relation to damp and moldy workplaces.International archives of occupational and environmental health · 2010
    Article
  14. Article
  15. Article
  16. Home and school environmental assessment and remediation.Current allergy and asthma reports · 2009
    Review
  17. Article
  18. Toward a comprehensive understanding of allergic lung disease.Transactions of the American Clinical and Climatological Association · 2009
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jay M PortnoySection of Allergy, Asthma, and Immunology, Children's Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA. jportnoy@cmh.edu
Charles S Barnes
Kevin Kennedy
Mercy Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal exposure is hypothesized (controversially) to contribute to asthma development and to trigger symptoms in patients with asthma. The ubiquity of environmental fungal exposure makes a careful review of evidence essential. Evidence that exposure to high concentrations of fungal spores, antigens, or metabolites is associated with asthma development is limited. However, because mechanisms of asthma genesis are poorly understood, so too are the mechanisms of this potential association. This association is not proof of causality. Stronger evidence supports the hypothesis that fungal exposure triggers symptoms in asthmatic individuals. Proposed mechanisms have been tested and correlations between exposure and symptoms demonstrated. Though some correlations remain speculative, controlled studies could test such hypotheses. Because asthma is common and fungal exposure is ubiquitous, it is surprising that asthmatics don't have more symptoms when exposed to fungi. Fortunately, symptoms are dose dependent, creating an opportunity to develop clinically effective interventions. Given the right guidance, even patients with severe asthma can create healthy indoor environments.

Indexed as

AllergensAnimalsAsthmaErgosterolFungiGlucansHumansHypersensitivityIrritantsMycotoxinsAllergensErgosterolGlucansIrritantsMycotoxins

Identifiers

PMID18377778
OpenAlexW2065169822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.